Figure 1From: Early innate immune events induced by prolonged cold ischemia exacerbate allograft vasculopathy Prolonged cold ischemia leads to earlier lesion formation. Aortic allografts were exposed to 20 min cold ischemia (left panel) or 60 min cold ischemia (right panel) and harvested between 3 wk and 6 wk. Representative sections from elastin stained aortic allografts harvested at (a) and (b) 3 wk post-transplant; (c) and (d) 4 wk post-transplant; (e) and (f) 6 wk post-transplant; (g) lesion size as mean ± SEM. n = 4 animals per time point. Orange arrows point to internal elastic lamina.Back to article page