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Ruptured hemiarch and descending thoracic aorta aneurysm: hybrid treatment

  • Alberto Settembrini2, 3Email author,
  • Daniela Mazzaccaro2, 3,
  • Silvia Stegher1,
  • Maria Teresa Occhiuto1,
  • Giovanni Malacrida1 and
  • Giovanni Nano1, 3
Journal of Cardiothoracic Surgery20127:66

DOI: 10.1186/1749-8090-7-66

Received: 24 January 2012

Accepted: 16 June 2012

Published: 10 July 2012

Abstract

Ruptured aortic arch aneurysm is a life threatening disease. Surgical repair has an high perioperative mortality rate and totally endovascular treatment is a challenge. Hybrid repair has been proposed as a valuable approach. We report the case of a patient with a contained rupture of aortic arch aneurysm. We treated him with a debranching of supraortic vessels with carotid-carotid and carotid-subclavian bypass and deployment of two enodgrafts in two different times. We consider hybrid treatment for arch and hemiarch a feasible option for aortic arch aneurysms in non emergent and in an emergency setting with an improvement in perioperative morbidity and mortality.

Background

Ruptured aortic arch aneurysm has a high mortality rate [1]. Management of this lesions is a challenge. Surgical repair is still an invasive procedure requiring arch replacement with hypo- thermic circulatory arrest and emergency procedure is associated with high periprocedural mortality rate (7-17%) and neurological complications (4-12%) [2, 3]. Endovascular stent-graft placement is safe and well standardized treatment in pathologies of descending aorta, also in emergency, but we have no many series about its use for aortic arch and hemiarch; if supra- aortic branches are involved, the placement of endovascular stent-graft requires fenestrations or surgical approaches to maintain cerebral perfusion [4, 5].

We describe a case of a rupture of aortic hemiarch aneurysm treated with hybrid procedure.

Case presentation

A 60 years old man affected by hypertension, hypercolesterolemia and chronic obstructive pulmonary disease (COPD), went to a hospital with a constrictive chest pain. He was haemodynamically stable and he did not have any signs of myocardial infarction (troponine was negative as electrocardiogram). So a CT angiography was performed, revealing a rupture of an aneurysm of left aortic hemiarch measuring a diameter of 8.8 cm. Due to the pathology and for haemodynamic stability, the patient was sent to our institution. When he arrived he was troubled and suffering. At clinical examination we did not find any pathological signs at the thorax and the abdomen; femoral and peripheral pulses were valid. There were no neurological deficits. At laboratory exams he had moderate anemia (10.2 g/dl), normal creatininemia (0.90 mg/dl) and tachycardia (100 beats) with right bundle branch block at electrocardiogram. A new CT angiography showed the contained rupture of the aneurysm. We evaluated the aneurysm was in zone 2, according to Ishimaru classification [6], of the arch, but it would be changed into a zone 1 for a safer deployment of the graft. The study of CT angio showed a proximal neck diameter of 32 mm and a distal landing zone of 28 mm with a short proximal neck that required a surgical debranching. Under general anaesthesia and electroencephalogram monitoring, a debranching of supraortic vessels was performed, avoiding median sternotomy; extranatomic carotid-carotid right to left bypass, with a retropharyngeal course, and a left carotid to subclavian bypass were done, followed by endovascular repair of the aneurysm with deployment of endoprosthesis Relay-BoltonTM 32/155 through femoral percutaneous approach. (Figure 1) There were no endoleaks at the completion angiography without any complication in puncture’s site. The patient was referred to Intensive Care Unit (ICU). In the first postoperative day the patient was extubated. He had no nerve injuries and neurological asymptomatic and vital signs were within normal limits. During the 2nd postoperative day he was clinically stable, but a left supraclavicular haematoma had grown up and chest pain was worsen with a diffused pulsatility in the left hemithorax. A CT angiography showed a new rupture of the aneurysm due to a type Ia endoleak for a dislocation of graft (Figure 2). The patient was taken to operating room to correct the lesion with deployment of endoprosthesis RelayTM 36/190 with free flow on innominate artery. Again, no endoleaks at the end of the procedure.
Figure 1

Deployment of the endograft and carotid-carotid-left subclavian bypass.

Figure 2

CT and angio images of displacement of the graft and enlargement of the sac.

The patient was discharged in 17th postoperative day and CT angiography was performed: it showed a complete exclusion of the sac. The CT angiography follow up was strict at 2, 6 and 36 months showing a progressive shrinkage of the sac (now the diameter is 4.63) (Figure 3). Echocolordoppler evaluation revealed the normal patency of supraortic bypasses at 36 months.
Figure 3

CT control after second operation: correct position of the graft and no leaks.

Discussion

The future of treatment of aortic arch pathologies is unclear. Since few years ago gold standard in the treatment of aortic arch pathology was surgery with cardio-pulmonary bypass and hypotermic cardiac arrest, but it carried a high mortality and morbidity with a significant incidence of neurologic injury. A totally endovascular solution for aortic arch is hard for involvement of supraortic trunks and the necessity of fenestration on the grafts or using chimney technique [7].

Recently, an hybrid treatment with a combined open and endovascular procedure has emerged and it has improved the chances in the treatment of pathologies of aortic arch, especially in the high-risk patient or in an emergent setting [8]. This technique consists of a surgical approach for revascularization of supra-aortic great vessels (using a supraortic transposition or debranching with bypasses) and endovascular deployment of an endograft.

This treatment allows both the preservation of the cerebral circulation and an optimal proximal landing zone and sealing of endovascular graft [8].

The rationale of the development of hybrid repairs is based on reduction of perioperative diseases avoiding cardio-pulmonary bypass and hypotermic cardiac arrest [7].

In literature we found different types of hybrid treatment of aortic arch pathology, but we did not find anything about the emergent treatment of a rupture hemiarch aneurysm. Szeto described a classification of hybrid repair dividing it into three types of repair based on aneurysm anatomy and landing zone suitability. But all the types require a multiple stage treatment and are long to do, so that they can’t be performed in emergency [7].

Our zone 2 ruptured lesion needed a supraortic reconstruction both to have a better landing zone and to avoid neurological adverse events. In emergency we did not have time to perform a multiple stage treatment because in this case we were between two problems: excluding the sac to avoid a worse evolution of the rupture and preventing any neurological accidents. We needed a fast surgical debranching for supraortic trunks to place safely the endograft [8].

Recently Joyeux et al. described a temporary extra anatomic bypass from femoral artery to supraortic trunks during the deployment of endograft and before performing sternotomy and debranching [9]. It could be another option for hybrid procedure but in our case surgical carotid-carotid bypass appears as a correct choice because we avoided the sternotomy, we allowed a patency of supraortic vessels without any risk of cerebral accident and we performed a well standardized and quite easy surgical intervention [4].

International guidelines suggest give some recommendation for the left subclavian artery (LSA) management and, in case of emergency, suggest that revascularization should be individualized and addressed. Our patient was haemodinamically stable with a tamponade rupture and we decided to perform the LSA revascularization considering how many affections could overcome if we did not perform it: neurological affections, the lack of preoperative evaluation on which vertebral artery was dominant and the steal syndrome [10]. We thought the risk of all of these affections could be increased by the emergency of intervention and the weak stability of the haemodynamic conditions [10, 11].

During the deployment, in both procedures, pressure control was very precise keeping values below 110 mmHg and a lowering cardiac beats (the mean value has been 90 bpm). However, about endograft, it is important to remember they are not designed for the deployment in aortic arch. In our case we had a displacement of the graft after the first operation. The graft used for aortic arch aneurysm are designed for descending aorta and so they are tubular and tend to straighten to come back to their natural shape. Further improvement are needed in the future to optimize the use of these graft for aortic arch lesions [7, 12].

Conclusion

Emergent hybrid treatment for aortic hemiarch is not still standardized and there is not a widespread use of this kind of treatment. We report our first experience with hybrid, combining supra-aortic branch trans position with endovascular stent-grafting in emergency. Currently the hybrid treatment for arch and hemiarch is evolving with an improvement in perioperative morbidity and mortality in non emergent cases in high risk patients [1, 13].

Even though this is just a case report and data are still limited and larger series are required to extend hybrid procedure to lower risk patients in non emergent cases, we deem that in case of rupture of aortic hemiarch aneurysm hybrid procedure could be a safe and effective treatment [14].

Consent

Our Institution and the patient provided Clinical Consent for the publication of this case.

Author’s contribution

AS: concept and design, writing the article. DM: critical revision of the article. SS: analysis and interpretation. MTO: critical revision. GM: final approval of the article. GN: obtaining funding, final approval of the article. All authors read and approved the final manuscript.

Declarations

Authors’ Affiliations

(1)
First Unit of Vasular Surgery, Policlinico San Donato
(2)
Postgraduate School in Vascular Surgery
(3)
Università di Milano

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Copyright

© Settembrini et al.; licensee BioMed Central Ltd. 2012

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.