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Table 5 Receiver operating characteristic curves for predicting and monitoring fluid responsiveness

From: Mixed venous O2 saturation and fluid responsiveness after cardiac or major vascular surgery

 

AUC

P

Cutoff

Sens.

Spec.

PPV

NPV

 

(95% confidence interval)

      

For increase in CI ≥15%

SvO2, %

0.65 (0.44 to 0.86)

0.17

77

    

Change in SvO2, %

0.73 (0.56 to 0.86)

0.007

2

77

73

87

57

GEDVI, mL/m2

0.67 (0.47 to 0.88)

0.10

899

68

70

81

54

Change in GEDVI, mL/m2

0.82 (0.65 to 1.0)

<0.001

13

95

60

82

86

For increase in SVI ≥15%

SvO2, %

0.60 (0.40 to 0.81)

0.29

77

87

50

74

70

Change in SvO2, %

0.68 (0.50 to 0.82)

0.04

2

78

64

78

64

GEDVI, mL/m2

0.58 (0.38 to 0.76)

0.48

899

69

62

69

62

Change in GEDVI, mL/m2

0.83 (0.65 to 0.94)

<0.001

92

75

92

92

75

For increase in CI ≥15% at high and low GEF

Change in SvO2, %

GEF >20%

0.57 (0.23 to 0.92)

0.68

3

0

71

0

42

GEF ≤20%

0.94 (0.81 to 1.0)

<0.001

2

92

100

100

95

GEDVI, mL/m2

GEF >20%

0.80 (0.53 to 1.0)

0.02

755

71

86

83

75

GEF ≤20%

0.81 (0.58 to 1.0)

0.008

1028

75

100

100

50

Change in GEDVI, mL/m2

GEF >20%

0.76 (0.47 to 0.94)

0.10

49

86

71

75

83

GEF ≤20%

0.92 (0.73 to 1.0)

<0.001

92

75

100

100

50