Figure 1

Time course of creatinine plasma levels in patients receiving levosimendan intraoperatively or on ICU and not requiring RRT. Postoperative creatinine plasma levels were significantly reduced when levosimendan was administered in the OR (p = 0.009). Values are expressed as means ± SD. Preop = preoperative; Surgery = ICU admission; POD 1 – 4 = first to fourth postoperative day; LEVO OR = start of levosimendan administration after anesthesia induction in the operating room; LEVO ICU = start of levosimendan administration after admission on ICU.