Unmatched study population | Matched study population | ||||||
---|---|---|---|---|---|---|---|
Parameter | All patients n = 288 (100%) | LS + n = 84 (29.17%) | LS - n = 204 (70.83%) | p-value | LS + n = 82 (33%) | LS - n = 164 (67%) | p-value |
Age [years]|; mean ± SD | 69 ± 11 | 68 ± 11 | 70 ± 11 | 0.16 | 67 ± 11 | 68 ± 10 | 0.62 |
Sex [females] n (%) | 70 (24) | 19 (23) | 51 (25) | 0.76 | 19 (23) | 41 (25) | 0.88 |
Body mass index [kg/m2] mean ± SD | 27 ± 7.0 | 27 ± 5.6 | 27 ± 7.5 | 0.71 | 27 ± 5.7 | 27 ± 8.2 | 0.81 |
Preoperative LVEF [%];mean ± SD | 26 ± 7.3 | 26 ± 7.0 | 25 ± 8.0 | 0.14 | 26 ± 10 | 27 ± 11 | 0.47 |
Preoperative renal impairment; n (%) • Stage 2 (GFR 85-120ml/min.) • Stage 3 (GFR 51-85ml/min.) • Stage 4 (GFR <51ml/min.) • Stage 5 (Dialysis) | 168 (58) 84 (29) 54 (32) 18 (11) 11 (6.5) | 49 (58) 13 (27) 20 (41) 10 (20) 6 (12) | 119 (58) 71 (60) 34 (29) 8 (6.8) 5 (4.2) | 0.013 | 47 (57) 13 (28) 20 (43) 9 (19) 5 (11) | 103 (63) 59 (57) 31 (30) 8 (7.8) 5 (4.9) | 0.16 |
Preoperative atrial fibrillation; n (%) | 96 (33) | 29 (34) | 67 (32) | 0.48 | 29 (38) | 57 (35) | 0.67 |
Preoperative cardiopulmonary resuscitation; n (%) | 14 (4.9) | 4 (4.8) | 10 (4.9) | 1.00 | 4 (4.9) | 9 (5.5) | 1.00 |
Preoperative invasive ventilation; n (%) | 22 (7.6) | 5 (6.0) | 17 (8.3) | 0.67 | 5 (6.1) | 15 (9.2) | 0.49 |
Preoperative use of inotropes and vasoactive drugs; n (%) • Epinephrine • Norepinephrine • Milrinone • Dobutamine | 48 (17) 12 (4.2) 18 (6.3) 4 (1.4) 14 (4.9) | 9 (11) 1 (1.2) 3 (3.6) 1 (1.2) 4 (4.8) | 39 (19) 11 (5.4) 15 (7.4) 3 (1.5) 10 (4.9) | 0.11 0.41 1.00 1.00 0.42 | 9 (11) 1 (1.3) 3 (3.7) 1 (1.2) 4 (4.9) | 23 (20) 9 (5.5) 14 (8.5) 2 (1.2) 8 (4.9) | 0.12 0.10 0.19 1.00 1.00 |
EuroSCORE II [%]; mean ± SD • Isolated CABG group • Valve/aortic surgery group • Combi group | 17.3 ± 16.4 14.3 ± 13.4 17.9 ± 19.8 21.4 ± 17.4 | 19.2 ± 16.4 17.8 ± 17.7 11.7 ± 10.2 23.0 ± 16.2 | 16.5 ± 16.4 12.9 ± 11.7 20.1 ± 21.8 20.4 ± 18.2 | 0.21 0.071 0.19 0.48 | 19.0 ± 16.6 15.8 ± 12.1 13.7 ± 10.0 20.1 ± 13.4 | 17.1 ± 17.3 12.6 ± 11.3 20.9 ± 22.8 21.4 ± 18.9 | 0.41 0.56 0.37 0.73 |
Type of Surgery; n (%) • Isolated CABG • Valve Surgery or Surgery on Thoracic aorta • Combination procedures | 138 (48) 46 (16) 99 (34) | 32 (38) 13 (15) 39 (46) | 106 (52) 38 (19) 60 (29) | 0.038 0.72 <0.01 | 32 (39) 12 (15) 38 (46) | 71 (43) 33 (20) 60 (37) | 0.76 0.16 0.19 |
Systolic blood pressure at induction of anaesthesia [mmHg]; median (IQR) | 113 (101–128) | 109 (98–127) | 115 (100–130) | 0.87 | 115 (101–123) | 119 (103–126) | 0.74 |
Diastolic blood pressure at induction of anaesthesia [mmHg]; median (IQR) | 69 (60–82) | 67 (59–81) | 70 (59–83) | 0.87 | 71 (61–87) | 71 (65–79) | 0.85 |
Extracorporeal circulation time [min.]; median (IQR) | 98 (79–108) | 93 (71–98) | 103 (81–112) | 0.24 | 114 ± 34 | 111 ± 26 | 0.58 |
Cardioplegic arrest time [min.]; median (IQR) | 67 (51–89) | 67 (50–90) | 67 (53–86) | 0.74 | 73 ± 30 | 72 ± 24 | 0.82 |