The effect of ulinastatin on acute kidney injury in patients undergoing off-pump cardiac bypass surgery

Table 2 Intraoperative and postoperative findings of patients with and without ulinastatin

	Control group (n = 200)	Ulinastatin group (n = 100)	P value
Blood loss (mL)	429.0 (300.0, 800.0)	450.0 (300.0, 500.0)	0.375
Fluid administration (mL)
Intraoperative period
Crystalloid	2650.0 (2100.0, 3250.0)	3100.0 (2540.0, 3900.0)	< 0.001*
Colloid	500.0 (0.0, 700.0)	500.0 (400.0, 550.0)	0.771
Albumin	0.0 (0.0, 200.0)	0.0 (0.0, 100.0)	0.356
Post-operative within 6 h
Crystalloid	1100.0 (945.0, 1355.0)	1092.0 (890.0, 1292.0)	0.348
Colloid	0.0 (0.0, 0.0)	0.0 (0.0, 0.0)	0.764
Albumin	100.0 (88.0, 100.0)	93.0 (70.0, 100.0)	0.014*
Post-operative within 24 h
Crystalloid	3835.0 (3373.0, 4230.0)	3605 (3235.0, 4126.0)	0.055
Colloid	0.0 (0.0, 0.0)	0.0 (0.0, 0.0)	0.829
Albumin	197.0 (95.0, 342.0)	100.0 (91.0, 258.0)	0.040*
Post-operative within 48 h
Crystalloid	5945.0 (5552.0, 6810.0)	5880.0 (5111.0, 6390.0)	0.053
Colloid	0.0 (0.0, 0.0)	0.0 (0.0, 0.0)	0.841
Albumin	250.0 (100.0, 414.0)	235.0 (100.0, 346.0)	0.260
Number of intraoperative hypotension event	1.45 ± 1.66	1.50 ± 1.71	0.807
RBC transfusion (unit)	0.860 ± 1.228	0.850 ± 1.140	0.946
Intraoperative urine (mL)	550.0 (385.0, 990.0)	905.0 (615.0, 1235.0)	0.002*
Post-operative urine within 6 h	860.0 (575.0, 1275.0)	975.0 (760.0, 1330.0)	0.079
Post-operative urine within 24 h	2315.0 (1880.0, 3400.0)	2565.0 (2015.0, 3270.0)	0.371
Post-operative urine within 48 h	4460.0 (3585.0, 5510.0)	4285.0 (3710.0, 5380.0)	0.516

Data are presented as number, mean ± standard deviation, and median (interquartile range)
P value* < 0.05 indicates statistical significance
Intraoperative hypotension is defined as SBP ≤ 80 mmHg or MAP ≤ 60 mmHg
RBC Red blood cell

ISSN: 1749-8090