Cardioprotective role of royal jelly in the prevention of celecoxib-mediated cardiotoxicity in adult male albino rats

Table 3 Effects of celecoxib administration (50 mg/kg/day, orally), and celecoxib plus royal jelly administration (300 mg/kg/day, orally) in comparison to the control group, on apoptotic and anti-apoptotic genes expression in male albino rats. Data are expressed as mean ± SD, n = 10/group

Groups	Apoptotic gene (Bax/ Gapdh %)	Anti-apoptotic gene (Bcl-2/Gapdh %)
Groups	Heart	Heart
1	1.00 ± 0.00^c	1.00 ± 0.02^a
2	6.94 ± 1.15^a	0.20 ± 0.07^c
3	2.40 ± 0.39^bc	0.68 ± 0.00^b

Group (1) received no drug (control). Group (2) received celecoxib (50 mg/kg/day, orally), for 30 successive days. Group (3) received celecoxib (50 mg/kg/day, orally) and royal jelly (300 mg/kg/day, orally) for 30 successive days. Means carrying different superscripts in the same column are significant at p < 0.05

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