Table 1 A review of PEHE cases who underwent surgery

Crotty et al., 2000

[15]

Four patients,

All male

55-71Y/O

Chest pain (3/4)

Dyspnea (3/4)

Productive cough & Fever (1/4)

Weight loss (1/4)

Thoracotomy and pleural decortication (3/4)

Video-assisted thoracoscopic pleural biopsy (1/4)

Not specified

Average 10 month

Al-Shraim et al., 2005 [16]

51 M

Dry cough and shortness of breath

Decortication & resection of the pleural tumor

Interferon α

> 24

Saqi et al., 2007 [17]

37 M

Dyspnea and pleuritic chest pain

Pleural decortication

A single cycle of carboplatin, etoposide, and avastin

2

Lee et al., 2008 [5]

31 F

Bilateral upper back pain

Thoracoscopic wedge resection of the right lower lobe of the lung

Adriamycin then switched to Mesna-Doxorubicin-

Ifosfamide-Dacarbazine (MAID) + radiotherapy of spinal lesions

10

Chou et al., 2011 [18]

42 M

Chest pain and productive cough

Pleurectomy

Chemotherapy and radiotherapy after 5 month due to metastatic bony and spine lesions

> 14

27 M

Dry cough, hoarseness and chest tenderness

Pleurectomy at 5 month

Radiotherapy and then doxorubicin and cisplatin at 5 month

18

Kim et al., 2011 [19]

46 F

Right-sided chest discomfort and cough

Decortication and visceral pleurectomy followed by complete pleurectomy and cytologic reduction to minimal disease

Carboplatin and etoposide

23

Lazarus et al., 2011 [20]

42 M

Cough, dyspnea, right sided back pain

Video-assisted thoracoscopic surgery (VATS), almost complete pleurectomy

Taxol and Bevacizumab

8

42 M

Cough, low-grade fever

Decortication

Carboplatin, etoposide, and bevacizumab

6

Yu et al., 2013 [11]

39 F

Progressive dyspnea

Radical resection of the mass and left pericardium

Carboplatine and etoposide

No evidence of recurrence at 14 month

Ha et al., 2014 [21]

71 M

Cough, dyspnea, fatigue and poor oral intake

Wedge resection

Scheduled for chemotherapy

Not specified

Apolinário et al., 2016 [22]

47 F

Chest

Pain and dyspnea

Pulmonary decortication and parietal pleurectomy

Doxorubicin, one cycle before death

6

Takenaka et al. 2020 [14]

62 M

Right chest pain and dyspnea on exertion

Extrapleural pneumonectomy due to extended disease

Pazopanib after recurrence in one month

3.5

Jebastin Thangaiah et al., 2021 [23]

39 F

Chest and back pain

Left lower lobe wedge resection

Clinical trial with Trametinib

> 15

Lavacchi et al., 2021 [13]

53 M

Chronic left hemithorax pain

Extrapleural pneumonectomy

Not specified

No radiological evidence of recurrent disease after 8 month

Hsu et al., 2022 [12]

35 M

Chronic non-productive cough

Extrapleural pneumonectomy

Radiation therapy after the surgery

Not concluded

Al-Nafisi et al., 2023 [24]

58 M

Incidental diagnosis in a lower back pain work up

VATS and pleural mass resection

Constant follow-up due to comorbidities

Not concluded

Pathak et al., 2023 [25]

73 F

Dyspnea, cough, and pleuritic

Chest pain

VATS with decortication

Chemo/radiation therapy was started after the study

Not concluded

Our case

39 F

Progressive dyspnea and left shoulder discomfort

Extrapleural pneumonectomy at 7 month

Mesna, Adriamycin, Ifosfamide, Dacarbazine (MAID) regimen

10