The association of regional block with intraoperative opioid consumption in patients undergoing video-assisted thoracoscopic surgery: a single-center, retrospective study

Table 3 Primary and secondary outcomes

	GA n = 42	TEA n = 42	TPVB n = 42	SAPB n = 42	P value
Intraoperative OME, mg	512 [450,630]	411 [360,540]*	384 [300,489]*	461 [381,540]	0.001
Sufentanil IV, ug	25 [20,30]	20 [20,30]	20 [15,30]	15 [10,20]	< 0.001
Remifentanil IV, ug	1420 [1200,1800]	1180 [920,1600]	1080 [800,1400]	1360 [1120,1600]	0.002
Tramadol IV, mg	0 [0,100]	0 [0,0]	0 [0,0]	0 [0,0]	< 0.001
Rescue analgesic during the first 72 h after surgery	18 (42.9)	15 (35.7)	12 (28.6)	7 (16.7)	0.069
Time-to-first rescue analgesic after surgery, h	18 [12,23]	16 [5,22]	18 [12,21]	18 [17,20]	0.718
Postoperative complications	1 (2.4)	4 (9.5)	5 (11.9)	0 (0)	0.154
Pneumonia	0 (0)	1 (2.4)	0 (0)	0 (0)
Pneumothorax	0 (0)	1 (2.4)	2 (4.8)	0 (0)
Chylothorax	0 (0)	1 (2.4)	2 (4.8)	0 (0)
Pleural effusion	1 (2.4)	1 (2.4)	0 (0)	0 (0)
Atrial fibrillation	0 (0)	0	1 (2.4)	0 (0)
PACU duration, min	45 [35,60]	34 [28,45]	30 [15,45]	44 [29,59]	0.007
Length of postoperative hospital stay	5 [4,5]	4 [4,6]	4 [3,5]	3 [3,4]	< 0.001

Continuous variables were expressed as the median [Interquartile range] and compared between groups will be performed using the Kruskal-Wallis H rank-sum test. Categorical variables were expressed as numbers (percentages), and comparisons between groups were performed using the chi-square test or Fisher’s exact test if a cell count was less than 5.*Bonferroni adjusted P < 0.05
Abbreviations: GA: General anesthesia withou regional block; TEA: Thoracic epidural analgesia combined with general anesthesia; TBVP: Thoracic paravertebral block combined with general anesthesia; SABP: Serratus anterior plane block combined with general anesthesia; OME: Oral Morphine Equivalents; PACU: Post Anesthesia Care Unit; NSAIDs: Non-Steroidal Anti-Inflammatory Drugs; PONV: Postoperative Nausea and Vomiting.

ISSN: 1749-8090