Skip to main content
Fig. 1 | Journal of Cardiothoracic Surgery

Fig. 1

From: Smoking behavior associated upregulation of SERPINB12 promotes proliferation and metastasis via activating WNT signaling in NSCLC

Fig. 1

SERPINB12 was significantly upregulated in NSCLC and was highly associated with smoking. (A) The volcano plot shows the differentially expressed genes in smokers with NSCLC. (B) The expression pattern of SERPINB12 in tumor and normal tissues analyzed by TCGA data. (C) The expression pattern of SERPINB12 in tumor and adjacent tumor tissues analyzed by qPCR using the collected tissue. (D) The expression profile of SERPINB12 in normal samples and NSCLC patients with or without a habit of smoking according to TCGA data. (E) The expression profile of SERPINB12 according to cigarette consumption. (F) The expression pattern of SERPINB12 in various pathologic stages. (G) The overall survival of lung cancer patients with high and low expression of SERPINB12. (H) The overall survival of smoking patients with high and low expression of SERPINB12. (I) The overall survival of nonsmoking patients with high and low expression of SERPINB12. * p < 0.05, ** p < 0.01, *** p < 0.001

Back to article page

Journal of Cardiothoracic Surgery

ISSN: 1749-8090

Contact us