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Table 2 Pathologic characteristics associated with sentinel lymph node detection

From: Clinicopathological factors associated with sentinel lymph node detection in non-small-cell lung cancer

 

SLN-negative group (n = 17)

SLN-positive group (n = 48)

p

Tumor size (cm)

≤ 1 cm

1.1 − 2 cm

2.1 − 3 cm

≥ 3.1 cm

1 (5.9)

7 (41.2)

7 (41.2)

2 (11.8)

12 (25.0)

22 (45.8)

8 (16.7)

6 (12.5)

0.13

Location

Central

Peripheral

2 (11.8)

15 (88.2)

5 (10.4)

43 (89.6)

0.88

Histology

Adenocarcinoma

Squamous cell carcinoma

Others

8 (47.1)

7 (41.2)

2 (11.8)

36 (75.0)

8 (16.7)

4 (8.3)

0.09

T stage

T1a

T1b

T1c

T2a

T2b

1 (5.9)

5 (29.4)

6 (35.3)

4 (23.5)

1 (5.9)

12 (25.0)

19 (39.6)

7 (14.6)

10 (29.8)

0 (0)

0.14

N stage

N1

N2

1 (5.9)

0 (0)

3 (6.3)

2 (4.2)

0.44

Stage

IA

IB

IIA

IIB

IIIA

11 (64.7)

4 (23.5)

1 (5.9)

1 (5.9)

0 (0)

36 (75.0)

7 (14.6)

1 (2.1)

2 (4.2)

2 (4.2)

0.74

Visceral pleural invasion

PL0 + PL1

PL2

2 (11.8)

0 (0)

4 (8.3)

1 (2.1)

0.88

Visceral pleural distance (cm)

0.55 ± 0.73

0.45 ± 0.57

0.5

STAS

9 (52.9)

19 (39.6)

0.34

Perineural neoplastic invasion

1 (5.9)

1 (2.1)

0.44

Vascular invasion

4 (23.5)

10 (20.8)

0.82

EGFR mutation

0 (0)

4 (8.3)

0.16

PD-L1 status

PD-L1 < 1%

PD-L1 1 − 49%

PD-L1 ≥ 50%

8 (47.1)

5 (29.4)

4 (23.5)

28 (63.6)

12 (27.3)

4 (9.1)

0.245

KRAS mutation

5 (29.4)

8 (16.7)

0.45

  1. Values are n (%) or mean (SD) unless otherwise indicated
  2. cm, centimeter; EGFR, epidermal growth factor receptor; KRAS, V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; PD-L1, Programmed death-ligand 1; PL, Pleural; SD, standard deviation; SLN, sentinel lymph node; STAS, Spread through air spaces