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Table 1 Patient Characteristics and predictors of severe thoracic aortic calcification

From: Predictive factors of thoracic aortic calcification in patients candidate for cardiac surgery

Predictor

TACS < 400

(n = 347)

TACS ≥ 400

(n = 209)

Univariate

Multivariable

OR (95% CI)

P value

OR (95% CI)

P value

Mean age, y

55.7 ± 10.6

67.3 ± 7.1

1.17 (1.14–1.20)

< 0.001

1.17 (1.14–1.21)

< 0.001

Female

131 (37.8)

84 (40.2)

0.90 (0.63–1.28)

0.567

-

-

BMI, kg/m2

27.5 ± 4.4

27.9 ± 4.3

1.02 (0.98–1.06)

0.298

-

-

Diabetes mellitus

107 (30.8)

85 (40.7)

1.54 (1.07–2.20)

0.018

1.70 (1.09–2.65)

0.019

Hypertension

155 (44.7)

127 (60.8)

1.92 (1.35–2.72)

< 0.001

1.31 (0.79–2.17)

0.300

Dyslipidemia

134 (38.6)

104 (49.8)

1.57 (1.11–2.23)

0.010

1.27 (0.77–2.21)

0.347

Family history of CAD

103 (29.8)

65 (31.4)

1.08 (0.74–1.57)

0.686

-

-

Opium Addiction

39 (11.2)

38(18.2)

1.75 (1.08–2.85)

0.023

1.87 (1.04–3.35)

0.037

Current Smoking

78 (22.5)

55 (26.3)

1.23 (0.83–1.83)

0.305

-

-

Recent MI

24 (6.9)

9 (4.3)

0.61 (0.28–1.33)

0.211

-

-

LVEF, %

47.4 ± 9.2

45.9 ± 9.5

0.98 (0.96-1.00)

0.069

0.98 (0.96–1.01)

0.124

PVD

8 (2.3)

16 (7.7)

3.51 (1.48–8.36)

0.005

2.86 (0.90–9.10)

0.075

Previous CVA

19 (5.5)

18 (8.6)

1.63 (0.83–3.18)

0.154

-

-

Renal Failure

36 (10.4)

28 (13.4)

1.33 (0.79–2.26)

0.286

-

-

Valve surgery Indication

33 (9.5)

29 (13.9)

1.53 (0.90–2.61)

0.115

-

-

  1. Data are presented frequency (percentage), or mean ± standard deviation
  2. The area under the ROC curve for aortic calcification was 83.5% (95% CI: 80.2–86.8%, P value < 0.001)
  3. TACS, thoracic aortic calcium score; OR, odds ratio; CI, confidence interval; BMI, body mass index; CAD, coronary artery disease; MI, myocardial infarction; LVEF, left ventricular ejection fraction; PVD, peripheral vascular disease; CVA, cerebrovascular accident; ROC, receiver operating characteristic