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Table 1 Baseline characteristics

From: Postoperative hyper-inflammation as a predictor of poor outcomes in patients with acute type A aortic dissection (ATAAD) undergoing surgical repair

Variables

Control (n = 281)

Poor outcome (n = 124)

P value

Age(year)

53.8 ± 13.4

55.3 ± 13.5

0.371

Gender male n (%)

217 (77.2)

93 (75.0)

0.626

BMI(kg/m2)

25.4 (23.3–28.4)

25.2 (20.9–27.7)

0.570

Medical history n (%)

Hypertension

271 (96.4)

116 (93.5)

0.193

Diabetes mellitus

50 (17.8)

30 (24.2)

0.136

COPD

98 (34.9)

45 (36.3)

0.784

Smoking

135 (48.0)

58 (46.8)

0.814

Heavy alcohol drinking

41 (14.6)

17 (13.7)

0.816

Liver diseases

12 (4.3)

1 (0.8)

0.068

Marfan syndrome

14 (5.0)

6 (4.8)

0.951

Cerebral infarction

12 (4.3)

5 (4.0)

0.912

Chronic renal failure

3 (1.1)

1 (0.8)

0.806

Ascending aortic diameter (cm)

4.7 (4.4–5.4)

5.1 (4.5–5.5)

0.003

Pre-operative PCT (ng/ml)

0.01 (0.01–0.1)

0.01 (0.01–0.1)

0.207

Pre-operative CRP (mg/L)

3.52 (1.14–7.8)

3.6 (1.5–6.0)

0.984

Pre-operative IL-6 (pg/ml)

34.7 (11.9–60.0)

40 (17.4–61.6)

0.205

Pre-operative SII

546 (153–1326)

539 (152–1512)

0.874

Pre-operative Neutrophile (× 109/L)

4.3 (1–9.2)

9.2 (4.8–13.0)

0.822

Pre-operative Lymphocyte (× 109/L)

1.0 (0.7–1.4)

0.9 (0.8–1.3)

0.556

Pre-operative Platelet (× 109/L)

155 (116–190)

153 (121–176)

0.776

Preoperative conditions n (%)

Bowel ischemia

0

7 (5.6)

< 0.001

Cerebral ischemia

0

42 (10.4)

< 0.001

Limb ischemia

0

51 (41.1)

< 0.001

Coronary artery involvement

7 (2.5)

6 (4.8)

0.217

Arch surgery n (%)

0.702

Total arch replacement

183 (65.2)

86 (69.4)

 

Hemi arch replacement

40 (14.2)

16 (12.9)

 

Arch stent

58 (20.6)

22 (17.7)

 

Root surgery n (%)

0.304

Bentall procedure

144 (51.2)

65 (52.4)

 

Wheat’s procedure

56 (25.7)

36 (29.0)

 

Reconstruction

81 (23.1)

23 (18.6)

 

Concomitant CABG n (%)

7 (2.5)

6 (4.8)

0.217

CPB time (min)

182 (158.5–220.5)

188 (163–228)

0.233

ACC time (min)

133 (110.5–169.0)

135 (120–175)

0.099

DHCA time (min)

33 (26–41)

31 (25–43)

0.594

  1. Median (Interquartile range); BMI Body mass index, COPD Chronic obstructive pulmonary disease, PCT Procalcitonin, CRP C-reactive protein, IL-6 interleukin-6, SII Systemic immune-inflammation index, CABG Coronary artery bypass graft, CPB Cardiopulmonary bypass, ACC Aortic cross-clamp, DHCA Deep hypothermia circulatory arrest