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Fig. 3 | Journal of Cardiothoracic Surgery

Fig. 3

From: Circ_0001786 facilitates gefitinib resistance and malignant progression in non-small cell lung cancer via miR-34b-5p/SRSF1

Fig. 3

circ_0001786 can bind with miR-34b-5p. (A) The putative binding sequence between circ_0001786 and miR-34b-5p. (B) The level of miR-34b-5p in NSCLC tissues was detected by qRT-PCR. (C) Correlation between miR-34b-5p and circ_0001786 level in 40 NSCLC tissues using Spearman analysis. (D) The miR-34b-5p expression in 16HBE, PC9, HCC827, PC9-GR and HCC827-GR cells was detected by qRT-PCR. (E) Dual-luciferase assay was introduced in 293 T cells to confirm the binding relationship between circ_0001786 and miR-34b-5p. *P < 0.05, **P < 0.01, ***P < 0.001

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