Table 1 Baseline clinical and treatment characteristics of the randomized participants (n = 179)

Demographics

 Age, mean (SD), y

62.2 ± 13.0

61.9 ± 13.2

62.5 ± 12.8

0.766

 Male

129(72.1)

62(69.7)

67(74.4)

0.173

 Female

50(27.9)

27(30.3)

23(25.6)

0.283

 BMI, mean (SD), kg/m²

24.98(3.07)

24.26(3.31)

25.57(3.82)

0.124

 Weight, mean (SD), kg

68.99 ± 10.89

67.91 ± 12.21

70.32 ± 8.10

0.349

Presenting characteristics, mean (SD)

 Heart rate, beat/min

82.56 ± 15.52

75.4 ± 12.54

91.5 ± 15.503

0.128

 Systolic blood pressure, mmHg

123.7 ± 22.84

120 ± 27.009

128.25 ± 19.19

0.624

Medical history

 Hypertension

81 (45.3)

38 (42.7)

43 (47.8)

0.531

 Hypercholesterolemia

51 (28.5)

27 (30.3)

24 (26.7)

0.323

 Diabetes mellitus

21 (11.7)

10 (11.2)

11 (12.2)

0.317

 Atrial fibrillation

11 (6.2)

6 (6.7)

5 (5.6)

0.673

 Renal impairment

7 (3.9)

3 (3.4)

4 (4.4)

0.783

Smoking

 Current

67 (37.4)

35 (39.3)

32 (35.6)

0.364

 Former (stopped > 3 mo)

16 (39.3)

9 (10.1)

7 (7.8)

0.247

 Never

96 (53.6)

45 (50.6)

51 (56.7)

0.155

Preexisting maintenance medication

 Aspirin

32 (17.9)

15 (16.9)

17 (18.9)

0.754

 Statin

60 (33.5)

31 (34.8)

29 (32.2)

0.813

 β-blocker

66 (36.9)

34 (38.2)

32 (35.6)

0.471

 ACE inhibitor/ARB

54 (30.2)

25 (28.1)

29 (32.2)

0.542

Killip class

 I

158 (88.3)

77 (86.5)

81 (90.0)

0.267

 II‒IV

21 (11.7)

12 (13.5)

9 (10.0)

0.361

TIMI risk score

 Low risk (0–3)

32 (17.9)

15 (16.9)

17 (18.9)

0.383

 Moderate risk (4–6)

115 (64.3)

56 (62.9)

59 (65.6)

0.186

 High risk (7–14)

32 (17.9)

18 (20.2)

14 (15.6)

0.369

Initial blood results on admission

 Glucose, mean (SD), mmol/L

7.50 ± 3.19

7.73 ± 3.46

7.27 ± 2.90

0.343

 Creatinine, mean (SD), μmol/L

75.71 ± 25.53

75.25 ± 26.29

76.17 ± 24.91

0.809

 Uric acid, mean (SD), μmol/L

365.00 ± 110.60

355.64 ± 99.66

374.25 ± 120.362

0.262

 Total cholesterol, mean (SD), mmol/L

4.981 ± 1.33

5.10 ± 1.34

4.86 ± 1.32

0.235

 Triglycerides, mean (SD), mmol/L

1.84 ± 2.10

1.57 ± 1.19

2.10 ± 2.69

0.089

 HDL-C, mean (SD), mmol/L

1.26 ± 0.30

1.31 ± 0.32

1.21 ± 0.28

0.022

 LDL-C, mean (SD), mmol/L

3.15 ± 1.06

3.24 ± 1.11

3.07 ± 1.01

0.279

 Creatine kinase isoenzyme, mean (SD), IU/L

190.60 ± 137.50

182.94 ± 138.52

198.56 ± 136.85

0.467

 Troponin I, median (IQR), ng/mL

4882.00 ± 13,801.00

6562.34 ± 16,067.71

4161.18 ± 13,312.99

0.732

 Platelet count, mean (SD), × 10⁹/L

215.90 ± 62.14

214.47 ± 52.02

217.35 ± 71.18

0.782

 Mean platelet volume, mean (SD), fL

10.93 ± 1.23

10.85 ± 1.10

11.00 ± 1.36

0.459

 Leukocyte count, mean (SD), × 10⁹/L

10.90 ± 3.28

11.00 ± 3.38

10.80 ± 3.20

0.717

 Neutrophil count, mean (SD), × 10⁹/L

8.64 ± 3.25

8.76 ± 3.36

8.52 ± 3.16

0.653

 Lymphocyte percentage, mean (SD), %

13.9 ± 7.1

13.9 ± 7.0

13.9 ± 7.4

0.967

 Neutrophil, mean (SD), %

77.7 ± 9.4

78.1 ± 9.1

77.2 ± 9.8

0.579

 Monocyte, mean (SD), %

7.7 ± 3.3

7.3 ± 3.3

8.1 ± 3.3

0.132

 Eosinophil, mean (SD), %

0.7 ± 0.1

0.7 ± 1.0

0.7 ± 1.1

0.703

 Basophil, mean (SD), %

0.2 ± 0.1

0.2 ± 0.1

0.2 ± 0.2

0.309