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Table 4 Procedure outcomes

From: Efficacy and safety of intracoronary pro-urokinase combined with low-pressure balloon pre-dilatation during percutaneous coronary intervention in patients with anterior ST-segment elevation myocardial infarction

 

Intracoronary pro-UK No. (%) of patients (n = 89)

Intracoronary pro-UK combined with pre-dilatation No. (%) of patients (n = 90)

P Value

TIMI thrombus grade at initial angiography

 0 (no thrombus)

8 (8.99)

8 (8.89)

0.927

 1–2 (definite, < ½ vessel diameter)

13 (14.6)

12 (13.3)

0.579

 3 (3, definite, > ½ but < 2 vessel diameters)

17 (19.1)

19 (21.1)

0.642

 4 (definite thrombus ≥ 2 vessel diameters)

5 (5.6)

7 (7.8)

0.769

 5 (total occlusion)

46 (51.7)

44 (48.9)

0.875

TIMI flow grade at initial angiography

 0 (no flow)

61 (68.5)

61 (67.8)

0.631

 1 (minimal flow)

12 (13.5)

14 (15.6)

0.611

 2 (slow but complete)

9 (10.1)

8 (8.9)

0.528

 3 (normal flow)

7 (7.87)

7(7.78)

0.827

TIMI flow grade after conventional PTCA procedure

 0 (no flow)

6 (6.7)

3 (3.3)

0.031

 1 (minimal flow)

11 (12.4)

4 (4.4)

0.021

 2 (slow but complete)

9 (10.1)

11 (12.2)

0.059

 3 (normal flow)

63 (70.8)

72 (80.0)

0.017

TMPG flow after PCI

 0

7 (7.9)

5 (5.6)

0.055

 1

13 (14.6)

6 (6.7)

0.027

 2

8 (9.0)

9 (10.0)

0.056

 3

61 (68.5)

70 (77.8)

0.013

Corrected TIMI frame count (CTFC)

27.42 ± 5.457

23.17 ± 6.328

0.036

Reperfusion syndrome

 Premature ventricular contraction

24 (27.0)

16 (17.8)

0.031

 Ventricular tachycardia

9 (10.1)

7 (7.8)

0.057

 Ventricular fibrillation

1 (1.1)

2 (2.2)

0.252

 Bradycardia

1 (1.1)

1 (1.1)

0.881

 Atrioventricular block

0 (0)

0 (0)

-

 Transient drop of blood pressure ≥ 30 mmHg

11 (12.4)

8 (8.9)

0.728

 Total

43 (48.3)

34 (37.8)

0.022

Necessity of other medical therapy for No-flow

 Nitroglycerin

29 (32.6)

17 (18.9)

0.028

 Sodium nitroprusside

13 (14.6)

11 (12.2)

0.337

 Verapamil

3 (3.4)

2 (2.2)

0.835

 Adenosine

4 (4.5)

6 (6.7)

0.649

 Aspiration thrombectomy

9 (10.1)

7 (7.8)

0.753

 Total

58 (65.2)

43 (47.8)

0.018

Resolution of ST-segment elevation

 30 min after PCI

  Complete (> 70%)

24 (27.0)

31 (34.4)

0.047

  Partial (30% to < 70%)

46 (51.7)

47 (52.2)

0.872

  None (< 30%)

19 (21.4)

12 (13.3)

0.034

90 min after PCI

 Complete (> 70%)

28 (31.5)

36 (40.0)

0.044

 Partial (30% to < 70%)

45 (50.6)

49 (54.4)

0.896

 None (< 30%)

16 (18.0)

5 (5.6)

0.026

Thrombosis and coagulation indexes

 Prothrombin time (PT), sec

12.7 ± 2.979

12.4 ± 1.733

0.546

 International Normalized Ratio (INR)

1.03 ± 0.317

0.99 ± 0.154

0.515

 D-Dimer, mg/L

1.71 ± 4.238

1.47 ± 1.404

0.798

 Fibrinogen degradation products (FDP), mg/L

3.23 ± 2.777

5.74 ± 4.629

0.069

 MPO-DNA, ng/mL

925.67 ± 93.23

938.88 ± 71.32

0.916

Bleeding events in hospital

 Gingival

9 (10.1)

7 (7.8)

0.925

 Hematuria

2 (2.3)

4 (4.5)

0.873

 Hemoptysis

0 (0)

0 (0)

-

 Gastrointestinal hemorrhage

2 (2.3)

2 (2.2)

0.912

 Cath access site bleeding

4 (4.5)

3 (3.3)

0.892

 Intraocular hemorrhage

1 (1.1)

0 (0)

-

 Epistaxis

3 (3.5)

4 (4.5)

0.851

 Others

1 (1.1)

0 (0)

-

 Total, n (%)

22 (24.7)

20 (22.2)

0.794