| Intracoronary pro-UK No. (%) of patients (n = 89) | Intracoronary pro-UK combined with pre-dilatation No. (%) of patients (n = 90) | P Value |
---|---|---|---|
TIMI thrombus grade at initial angiography | |||
 0 (no thrombus) | 8 (8.99) | 8 (8.89) | 0.927 |
 1–2 (definite, < ½ vessel diameter) | 13 (14.6) | 12 (13.3) | 0.579 |
 3 (3, definite, > ½ but < 2 vessel diameters) | 17 (19.1) | 19 (21.1) | 0.642 |
 4 (definite thrombus ≥ 2 vessel diameters) | 5 (5.6) | 7 (7.8) | 0.769 |
 5 (total occlusion) | 46 (51.7) | 44 (48.9) | 0.875 |
TIMI flow grade at initial angiography | |||
 0 (no flow) | 61 (68.5) | 61 (67.8) | 0.631 |
 1 (minimal flow) | 12 (13.5) | 14 (15.6) | 0.611 |
 2 (slow but complete) | 9 (10.1) | 8 (8.9) | 0.528 |
 3 (normal flow) | 7 (7.87) | 7(7.78) | 0.827 |
TIMI flow grade after conventional PTCA procedure | |||
 0 (no flow) | 6 (6.7) | 3 (3.3) | 0.031 |
 1 (minimal flow) | 11 (12.4) | 4 (4.4) | 0.021 |
 2 (slow but complete) | 9 (10.1) | 11 (12.2) | 0.059 |
 3 (normal flow) | 63 (70.8) | 72 (80.0) | 0.017 |
TMPG flow after PCI | |||
 0 | 7 (7.9) | 5 (5.6) | 0.055 |
 1 | 13 (14.6) | 6 (6.7) | 0.027 |
 2 | 8 (9.0) | 9 (10.0) | 0.056 |
 3 | 61 (68.5) | 70 (77.8) | 0.013 |
Corrected TIMI frame count (CTFC) | 27.42 ± 5.457 | 23.17 ± 6.328 | 0.036 |
Reperfusion syndrome | |||
 Premature ventricular contraction | 24 (27.0) | 16 (17.8) | 0.031 |
 Ventricular tachycardia | 9 (10.1) | 7 (7.8) | 0.057 |
 Ventricular fibrillation | 1 (1.1) | 2 (2.2) | 0.252 |
 Bradycardia | 1 (1.1) | 1 (1.1) | 0.881 |
 Atrioventricular block | 0 (0) | 0 (0) | - |
 Transient drop of blood pressure ≥ 30 mmHg | 11 (12.4) | 8 (8.9) | 0.728 |
 Total | 43 (48.3) | 34 (37.8) | 0.022 |
Necessity of other medical therapy for No-flow | |||
 Nitroglycerin | 29 (32.6) | 17 (18.9) | 0.028 |
 Sodium nitroprusside | 13 (14.6) | 11 (12.2) | 0.337 |
 Verapamil | 3 (3.4) | 2 (2.2) | 0.835 |
 Adenosine | 4 (4.5) | 6 (6.7) | 0.649 |
 Aspiration thrombectomy | 9 (10.1) | 7 (7.8) | 0.753 |
 Total | 58 (65.2) | 43 (47.8) | 0.018 |
Resolution of ST-segment elevation | |||
 30 min after PCI | |||
  Complete (> 70%) | 24 (27.0) | 31 (34.4) | 0.047 |
  Partial (30% to < 70%) | 46 (51.7) | 47 (52.2) | 0.872 |
  None (< 30%) | 19 (21.4) | 12 (13.3) | 0.034 |
90Â min after PCI | |||
 Complete (> 70%) | 28 (31.5) | 36 (40.0) | 0.044 |
 Partial (30% to < 70%) | 45 (50.6) | 49 (54.4) | 0.896 |
 None (< 30%) | 16 (18.0) | 5 (5.6) | 0.026 |
Thrombosis and coagulation indexes | |||
 Prothrombin time (PT), sec | 12.7 ± 2.979 | 12.4 ± 1.733 | 0.546 |
 International Normalized Ratio (INR) | 1.03 ± 0.317 | 0.99 ± 0.154 | 0.515 |
 D-Dimer, mg/L | 1.71 ± 4.238 | 1.47 ± 1.404 | 0.798 |
 Fibrinogen degradation products (FDP), mg/L | 3.23 ± 2.777 | 5.74 ± 4.629 | 0.069 |
 MPO-DNA, ng/mL | 925.67 ± 93.23 | 938.88 ± 71.32 | 0.916 |
Bleeding events in hospital | |||
 Gingival | 9 (10.1) | 7 (7.8) | 0.925 |
 Hematuria | 2 (2.3) | 4 (4.5) | 0.873 |
 Hemoptysis | 0 (0) | 0 (0) | - |
 Gastrointestinal hemorrhage | 2 (2.3) | 2 (2.2) | 0.912 |
 Cath access site bleeding | 4 (4.5) | 3 (3.3) | 0.892 |
 Intraocular hemorrhage | 1 (1.1) | 0 (0) | - |
 Epistaxis | 3 (3.5) | 4 (4.5) | 0.851 |
 Others | 1 (1.1) | 0 (0) | - |
 Total, n (%) | 22 (24.7) | 20 (22.2) | 0.794 |