Table 2 Blood loss, transfusion requirement, laboratory values prior to and following rFVIIa administration
| Â | Before rFVIIa Treatment | After rFVIIa Treatment | p Value |
|---|---|---|---|
Blood Loss (ml/hr) | 698 ± 285 | - |  |
6 Hour Blood Loss (ml/hr) | - | 186 ± 146 | 0.001* |
12 Hour Blood Loss (ml/hr) | - | 136 ± 127 | <0.001* |
Packed Red Cells (Units) | 16.9 ± 13.3 | 7.1 ± 6.9 | 0.037 |
Single Donor Platelets (Units) | 4.0 ± 2.8 | 2.1 ± 2.2 | 0.024 |
FFP (Units) | 13.1 ± 8.2 | 4.1 ± 4.9 | <0.001 |
Cryoprecipitate (Units) | 6.3 ± 6.3 | 0.3 ± 0.6 | 0.006 |
Hematocrit | 0.27 ± 0. 79 | 0.29 ± 0.53 | 0.175 |
Platelet Count (x103/dL) | 116 ± 71 | 122 ± 51 | 0.379 |
PT (seconds) | 21.4 ± 4.8 | 14.9 ± 3.5 | <0.001 |
INR | 2.34 ± 0.91 | 1.44 ± 0.93 | 0.001 |
PTT (seconds) | 83.8 ± 43.4 | 53.7 ± 16.8 | 0.030 |