Skip to main content

Table 2 Blood loss, transfusion requirement, laboratory values prior to and following rFVIIa administration

From: Use of activated recombinant factor VII for severe coagulopathy post ventricular assist device or orthotopic heart transplant

  Before rFVIIa Treatment After rFVIIa Treatment p Value
Blood Loss (ml/hr) 698 ± 285 -  
6 Hour Blood Loss (ml/hr) - 186 ± 146 0.001*
12 Hour Blood Loss (ml/hr) - 136 ± 127 <0.001*
Packed Red Cells (Units) 16.9 ± 13.3 7.1 ± 6.9 0.037
Single Donor Platelets (Units) 4.0 ± 2.8 2.1 ± 2.2 0.024
FFP (Units) 13.1 ± 8.2 4.1 ± 4.9 <0.001
Cryoprecipitate (Units) 6.3 ± 6.3 0.3 ± 0.6 0.006
Hematocrit 0.27 ± 0. 79 0.29 ± 0.53 0.175
Platelet Count (x103/dL) 116 ± 71 122 ± 51 0.379
PT (seconds) 21.4 ± 4.8 14.9 ± 3.5 <0.001
INR 2.34 ± 0.91 1.44 ± 0.93 0.001
PTT (seconds) 83.8 ± 43.4 53.7 ± 16.8 0.030
  1. * p-value calculated as compared to blood loss before rVIIa administration