Augmentation index assessed by applanation tonometry is elevated in Marfan Syndrome

Table 3 Multivariate analysis of determinants of augmentation index, pulse wave velocity and aortic root size

Dependent variable	Independent variable	R-square	Standardised β-coefficient	p
Carotid AIx
	Presence of MFS	0.34	-0.63	<0.001
	Age	0.66	-0.57	<0.001
	Height	0.81	0.40	0.002
PWV
	Age	0.50	0.47	0.007
	MAP	0.61	0.47	0.008
	Presence of MFS	0.72	0.34	0.022
Aortic root size
	Presence of MFS	0.69	0.90	<0.001
	PWV	0.82	0.50	<0.001
	Carotid AIx	0.88	0.33	0.012
Aortic root/BSA
	Presence of MFS	0.76	0.87	<0.001

AIx, augmentation index. MAP, mean arterial pressure. PWV, pulse wave velocity. MFS, Marfan Syndrome. Aortic root size is at sinus of Valsalva. BSA is adjustment for body surface area.

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