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Table 4 Change from baseline haemodynamic values in response to GTN

From: Augmentation index assessed by applanation tonometry is elevated in Marfan Syndrome

  

Control (n = 10)

MFS (n = 10)

  

Mean change

p

Mean change

p

Heart rate, bpm

0.6 (3.6)

NS

2.7 (6.1)

NS

Mean arterial pressure, mmHg

-7.0 (5.3)

0.002

-4.1 (8.4)

NS

Pulse pressure, mmHg

Brachial

0.5 (9.4)

NS

5.1 (8.2)

NS

 

Carotid

0.4 (10.1)

NS

1.1 (6.0)

NS

Augmentation index, %

Radial

-14.7 (13.1)

0.006

-21.8 (12.1)

0.0003

 

Carotid

-8.7 (8.2)

0.008

-10.8 (10.8)

0.011

Aortic pulse wave velocity, m/s

-0.1 (0.5)

NS

0.1 (0.5)

NS

  1. Values are mean (SD)