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Table 5 Hazard Ratios for death at any time after registration for CABG for treated patients relative to untreated patients and for post-operative death for patients who had surgery within target times relative to those who had surgery after target times (figures in brackets are 95-percent confidence interval)
| Semi-urgent group | Non-urgent group | |
|---|---|---|
| Overall survival, time-dependent treatment effect* | ||
| No. of deaths/no. of patients | ||
| Treated patients | 517/5,792 | 95/1,524 |
| Untreated patients | 152/541 | 69/363 |
| Model I, Treatment indicator | ||
| Treated vs Untreated | ||
| Unadjusted hazard ratio | 0.53 (0.43–0.65) | 0.42 (0.30–0.59) |
| Adjusted hazard ratio | 0.54 (0.44–0.66) | 0.45 (0.32–0.63) |
| Model II, Treatment by target time | ||
| Early Surgery vs Untreated | ||
| Unadjusted hazard ratio | 0.47 (0.37–0.59) | 0.35 (0.23–0.55) |
| Adjusted hazard ratio | 0.45 (0.36–0.58) | 0.36 (0.23–0.56) |
| Late Surgery vs Untreated | ||
| Unadjusted hazard ratio | 0.58 (0.47–0.73) | 0.47 (0.32–0.68) |
| Adjusted hazard ratio | 0.61 (0.49–0.76) | 0.51 (0.35–0.74) |
| Model III, Treatment by target time and admission type | ||
| Early Surgery vs Untreated | ||
| Unadjusted hazard ratio | 0.47 (0.37–0.60) | 0.32 (0.20–0.51) |
| Adjusted hazard ratio | 0.45 (0.36–0.58) | 0.33 (0.20–0.53) |
| Late Surgery vs Untreated | ||
| Unadjusted hazard ratio | 0.58 (0.46–0.73) | 0.46 (0.32–0.67) |
| Adjusted hazard ratio | 0.61 (0.48–0.76) | 0.51 (0.35–0.74) |
| Unplanned Emergency vs Untreated | ||
| Unadjusted hazard ratio | 0.51 (0.31–0.84) | 0.80 (0.37–1.76) |
| Adjusted hazard ratio | 0.52 (0.32–0.87) | 0.73 (0.33–1.63) |
| Long-term post-operative survival† | ||
| No. of deaths/follow-up yrs | ||
| Early Surgery | 153/8,409 | 31/2,121 |
| Late Surgery | 303/13,883 | 64/3,648 |
| Unadjusted hazard ratio | 0.85 (0.70–1.03) | 0.84 (0.55–1.29) |
| Adjusted hazard ratio | 0.79 (0.65–0.96) | 0.86 (0.55–1.33) |
