Table 1 Clinical, radiographic and demographic features of nine patients with suspected cancer recurrence in whom endobronchial ultrasound transbronchial needle aspiration detected granulomatous inflammation.
| Age Sex Race | Oncological History Remission (yrs since initial diagnosis) | Chemotherapy | Lymph node Characteristics | Granuloma at other sites | Microbiologic Studies* | Treatment | Follow-up (months) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Station [8] | Size mm | PET +ve | Culture (n) | Staining | Serology | ||||||
|
1 56F C |
Breast Cancer Neadjuvant Chemotherapy |
Paclitaxel Lapatinib |
7 11R |
14 7 | - | No | P | N | N |
MAC Infection Rifabutin Ethambutol Clarithromycin | Radiographical and clinical improvement on antimycobacterial therapy |
|
2 28F C |
Melanoma (2) | No |
4R 7 |
7 13 | - | No | N (1) | N | - | None | No symptoms (11) |
|
3 49M H |
Hodgkin's Lymphoma Stage 1a (8) | No | 11R | 14 | Yes | No | N (2) | N | - | None |
No symptoms Node PET uptake and CT size reduced (6) |
|
4 56F AA |
GI Stromal Tumor (1) | Imatimib | 4R | 17 | - | TBBX** | N (1) | N | - |
Inhaled Fluticasone |
Productive Cough Progressive Pulmonary Infiltrates (12) |
|
5 61F C |
NSCLC T2N2M0 (1) |
Carboplatin Docetaxel | 11R | 9 | Yes | No | N (1) | N | - |
Inhaled Fluticasone |
Chronic cough Stable CT-PET (6) |
|
6 63M C |
Melanoma (4) | No |
2R 7 |
10 11 |
Yes Yes | Lymphocytic Meningitis** | N (3) | N | N |
Prednisone For neurosarcoidosis |
Neurological Symptoms No pulmonary symptoms Node PET uptake and CT size reduced (15) |
|
7 66M C |
Multiple Myeloma (3) |
Melphalan Thalidomide Lenalidomide | 11R | 11 | Yes |
EBBX** TBBX | N (2) | N | N | None |
No symptoms Stable CT-PET (8) |
|
8 68F AA |
Endometrial Cancer (2) |
Docetaxel Carboplatin Imatimib |
7 11R |
13 10 |
Yes Yes | No** | N (1) | N | - | None |
No symptoms Stable CT-PET Intraabdominal cancer Recurrence (9) |
|
9 77M C |
Colorectal Cancer (3) |
Cisplatin Capecitabine | 7 | 10 | - | No** | N (2) | N | - | None |
No symptoms Stable CT (10) |