Table 1 Clinical, radiographic and demographic features of nine patients with suspected cancer recurrence in whom endobronchial ultrasound transbronchial needle aspiration detected granulomatous inflammation.
Age Sex Race | Oncological History Remission (yrs since initial diagnosis) | Chemotherapy | Lymph node Characteristics | Granuloma at other sites | Microbiologic Studies* | Treatment | Follow-up (months) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Station [8] | Size mm | PET +ve | Â | Culture (n) | Staining | Serology | Â | Â |
1 56F C | Breast Cancer Neadjuvant Chemotherapy | Paclitaxel Lapatinib | 7 11R | 14 7 | - | No | P | N | N | MAC Infection Rifabutin Ethambutol Clarithromycin | Radiographical and clinical improvement on antimycobacterial therapy |
2 28F C | Melanoma (2) | No | 4R 7 | 7 13 | - | No | N (1) | N | - | None | No symptoms (11) |
3 49M H | Hodgkin's Lymphoma Stage 1a (8) | No | 11R | 14 | Yes | No | N (2) | N | - | None | No symptoms Node PET uptake and CT size reduced (6) |
4 56F AA | GI Stromal Tumor (1) | Imatimib | 4R | 17 | - | TBBX** | N (1) | N | - | Inhaled Fluticasone | Productive Cough Progressive Pulmonary Infiltrates (12) |
5 61F C | NSCLC T2N2M0 (1) | Carboplatin Docetaxel | 11R | 9 | Yes | No | N (1) | N | - | Inhaled Fluticasone | Chronic cough Stable CT-PET (6) |
6 63M C | Melanoma (4) | No | 2R 7 | 10 11 | Yes Yes | Lymphocytic Meningitis** | N (3) | N | N | Prednisone For neurosarcoidosis | Neurological Symptoms No pulmonary symptoms Node PET uptake and CT size reduced (15) |
7 66M C | Multiple Myeloma (3) | Melphalan Thalidomide Lenalidomide | 11R | 11 | Yes | EBBX** TBBX | N (2) | N | N | None | No symptoms Stable CT-PET (8) |
8 68F AA | Endometrial Cancer (2) | Docetaxel Carboplatin Imatimib | 7 11R | 13 10 | Yes Yes | No** | N (1) | N | - | None | No symptoms Stable CT-PET Intraabdominal cancer Recurrence (9) |
9 77M C | Colorectal Cancer (3) | Cisplatin Capecitabine | 7 | 10 | - | No** | N (2) | N | - | None | No symptoms Stable CT (10) |