Possible roles of Epstein-Barr virus in Castleman disease

Table 2 Demographics and Results of EBV Detection

Cases	Age (year)	Gender	Location	Histologic type	Greatest diameter of lesion (cm)	EBV PCR EBNA-2/EBER	EBV ISH	Vascularity
1	25	M	left neck	HV	5	+/+	IF	L
2	21	M	left neck	HV	5	+/+	IF	L
3	26	F	left neck	HV	5	+/+	GC	L
4	24	M	mediastinum	HV	6	+/+	IF	L
5	39	F	mediastinum	HV	1.5	+/+	GC	L
6	17	M	mediastinum	HV	5.7	+/+	IF	L
7	33	F	retroperitoneum	mixed	8	+/+	IF	L
8	26	M	Left neck	HV	2	+/+	GC	H
9	9	F	left neck	HV	5.5	+/+	GC	H
10	52	M	Left axilla	HV	1.5	+/+	GC	H
11	19	F	Left neck	HV	3	+/+	GC	H
12	52	F	left axilla	HV	2	+/+	GC	H
13	68	M	right axilla	HV	3	+/+	GC	H
14	50	M	left neck	HV	3	+/+	GC	H
15	33	F	mesocolic lymph node	HV	5	+/+	GC	H
16	32	F	retroperitoneum	HV	5.6	+/+	GC	H
17	19	M	mediastinum	HV	7	+/+	IF	L
18	39	F	mediastinum	HV	5	+/+	GC	H
19	53	M	bil axilla, bil inguinal	PC	4	+/+	IF	-

M: male; F; female; HV: hyaline-vascular type; PC: plasma cell type; EBV PCR: results of polymerase chain reaction, + stands for positive; EBV ISH: localization of Epstein-Barr virus detected by in-situ hybridization, GC means signals within germinal centers, IF represents signals detected in inter-follicular space; H and L indicate highly vascular and less vascular CD.

ISSN: 1749-8090