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Table 3 Risk factors associated with major complications in univariate analysis

From: UK pneumonectomy outcome study (UKPOS): a prospective observational study of pneumonectomy outcome

Risk factors

Numbers

Odds ratio (95%CI)

Age

312

1.07 (1.03, 1.10; P < 0.001)

ASA: ≥ P3 vs < P3

137, 173

1.9 (1.1, 3.0; P = 0.01)

DLCO mmol/min/kPa

153

0.76 (0.62, 0.92; P = 0.006)

Epidural vs paravertebral

187,90

1.8 (1.0,3.2; P = 0.05)

FEV1 L

309

0.67 (0.45, 1.00; P = 0.05)

FEV1 % predicted

308

1.00 (0.98,1.01; P = 0.7)

ppo FEV1 % predicted

306

0.99 (0.96,1.01; P = 0.4)

DLCO % predicted

154

0.99 (0.97,1.01; P = 0.13)

ppo DLCO % predicted

162

0.97 (0.93,1.01; P = 0.11)

Preop. O2 saturation on air: ≤ 94 vs > 94%

26, 235

2.3 (1.0, 5.2; P = 0.04)

One lung ventilation: (hours)

294

1.09 (0.99, 1.20; P = 0.1)

Plateau pressure during one lung ventilation: ≥ 25 vs < 25 cmH2O

254

1.5 (0.8, 2.7; P = 0.2)

Right vs left operations

110, 199

1.5 (0.9, 2.5; P = 0.08)

Fluid positive balance

272,19

0.9 (0.3, 2.5; P = 0.9)

Planned vs Converted

208,102

1.3 (0.8,2.2; P = 0.3)

Gender: Male vs Female

209,101

1.2 (0.7,2.0; P = 0.4)

Stump closure: staples vs sutures

249,36

1.1 (0.5,2.3; P = 0.9)

Smoking history: yes vs no

286,25

1.2 (0.5,3.0; P = 0.7)

Neo-adjuvant therapy: yes vs no

33,270

0.5 (0.2,1.1; P = 0.1)