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Table 4 Genetic Polymorphisms and occurrence of cardiac adverse events

From: Gene polymorphisms in APOE, NOS3, and LIPC genes may be risk factors for cardiac adverse events after primary CABG

    

Freedom from [%] at

Factor

Definition

n

Outcome

5 years

10 years

15 years

P

eNos

bb

141

Reintervention

93.9

88.7

75.9

0.041

4ab

aa/ab

51

 

87.5

67.9

62.7

 
 

bb

141

Combined

89.3

56.0

13.2

0.042

 

aa/ab

51

 

80.4

40.6

5.1

 

ApoE

2 3/3 3/3 4

182

Reintervention

92.3

84.5

75.1

0.001

 

2 4/4 4

10

 

90.0

64.3

32.1

 

LIPC

WW/WM

144

Reoperation

96.4

74.6

27.5

0.049

 

MM

48

 

89.5

54.5

9.9

 
  1. See Additional File 1for abbreviations of polymorphisms. M: Mutation; W: Wildtype. Significant differences are in italics (p < 0.05) or bold (p < 0.01) print.