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Table 2 Preoperative patient characteristics of patients developing DSI and control group

From: The concept of negative pressure wound therapy (NPWT) after poststernotomy mediastinitis – a single center experience with 54 patients

Patient characteristics, preoperative

Mediastinitis group

Control group

P-value of univariate comparisons

Male gender

43 (81%)

3189 (69%)

< 0,05

Age [years]

67,9 ± 1,4

67,8 ± 0,15

n.s.

Body height [cm]

168,7 ± 1,2

170 ± 0,12

n.s.

Body weight [kg]

88,9 ± 2,1

80,7 ± 0,2

< 0,001

Body-mass-index

31,3 ± 0,6

27,9 ± 0,07

< 0,001

Diabetes, oral

14 (26%)

851 (18%)

< 0,05

Diabetes, insulin-dependent

12 (22%)

549 (12%)

< 0,05

Ejection fraction [%]

54 ± 3,7

58 ± 0,4

n.s.

Hemoglobin, preoperative [g/dl]

13,5 ± 0,2

13,3 ± 0,02

n.s.

Hematocrit, preoperative [%]

40,3 ± 0,7

39,4 ± 0,1

n.s.

Leukocytes, preoperative [k/UL]

8,4 ± 0,7

7,8 ± 0,1

n.s.

Serum creatinine, preoperative [mg/dl]

1,2 ± 0,1

1,2 ± 0,01

n.s.

Creatinine kinase MB, preoperative [U/l]

21 ± 16,1

28,7 ± 2,0

n.s.

Chronic obstructive pulmonary disease

20 (38%)

918 (20%)

<0,01

Reduced ejection fraction

24 (44%)

1620 (34%)

P = 0,11

EuroSCORE

5,7 ± 0,4

5,9 ± 0,05

n.s.

CRP, preoperative [mg/l]

16,5 ± 3,9

11,4 ± 0,4

P = 0.19

  1. According to El Oakley and Wright [8] mediastinitis is defined as wound infection associated with sternal osteomyelitis with or without infected retrosternal space. Incremental risk factors for mediastinitis are diabetes, obesity, and the requirement of immunosuppressive agents. Failed therapeutic trial includes any surgical intervention with intent to treat mediastinitis.