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Table 2 Preoperative patient characteristics of patients developing DSI and control group

From: The concept of negative pressure wound therapy (NPWT) after poststernotomy mediastinitis – a single center experience with 54 patients

Patient characteristics, preoperative Mediastinitis group Control group P-value of univariate comparisons
Male gender 43 (81%) 3189 (69%) < 0,05
Age [years] 67,9 ± 1,4 67,8 ± 0,15 n.s.
Body height [cm] 168,7 ± 1,2 170 ± 0,12 n.s.
Body weight [kg] 88,9 ± 2,1 80,7 ± 0,2 < 0,001
Body-mass-index 31,3 ± 0,6 27,9 ± 0,07 < 0,001
Diabetes, oral 14 (26%) 851 (18%) < 0,05
Diabetes, insulin-dependent 12 (22%) 549 (12%) < 0,05
Ejection fraction [%] 54 ± 3,7 58 ± 0,4 n.s.
Hemoglobin, preoperative [g/dl] 13,5 ± 0,2 13,3 ± 0,02 n.s.
Hematocrit, preoperative [%] 40,3 ± 0,7 39,4 ± 0,1 n.s.
Leukocytes, preoperative [k/UL] 8,4 ± 0,7 7,8 ± 0,1 n.s.
Serum creatinine, preoperative [mg/dl] 1,2 ± 0,1 1,2 ± 0,01 n.s.
Creatinine kinase MB, preoperative [U/l] 21 ± 16,1 28,7 ± 2,0 n.s.
Chronic obstructive pulmonary disease 20 (38%) 918 (20%) <0,01
Reduced ejection fraction 24 (44%) 1620 (34%) P = 0,11
EuroSCORE 5,7 ± 0,4 5,9 ± 0,05 n.s.
CRP, preoperative [mg/l] 16,5 ± 3,9 11,4 ± 0,4 P = 0.19
  1. According to El Oakley and Wright [8] mediastinitis is defined as wound infection associated with sternal osteomyelitis with or without infected retrosternal space. Incremental risk factors for mediastinitis are diabetes, obesity, and the requirement of immunosuppressive agents. Failed therapeutic trial includes any surgical intervention with intent to treat mediastinitis.