Demonstration of the histopathological and immunohistochemical effects of a novel hemostatic agent, ankaferd blood stopper, on vascular tissue in a rat aortic bleeding model

Table 1 Light microscopical and immunohistochemical findings in the rats abdominal aorta on the operation day

	Group I (ABS)	Group II (Plain gauze)	P
Histopathological changes
Inflammatory reaction	1.0 ± 0.5	1.0 ± 0.6	0.7
Necrosis	none	none	N/A
Endothelial cell loss	1.0 ± 0.3	1.1 ± 0.4	0.5
Fibrin plug formation/Erythrocyte aggregation	1.5 ± 0.6	0.18 ± 0.4	0.0001
Immunohistochemical changes
e-NOS staining	1.9 ± 0.7	1.1 ± 0.4	0.0001

ISSN: 1749-8090