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Table 2 Systematic review of the English literature on mitral valve surgery for (isolated) MR caused by Libman-Sacks endocarditisa

From: Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature

Reference Year
published
Gender/
Age (years)
SLE and/
or APS
Years of SLE
and/or APS
Steroids MR
gradeb
MVR/MVP Surgical procedure Follow-up
Myerowitz et al [48] 1974 F/22 SLE 3 yes 4+ MVR Reis-Hancock porcine bioprosthesis alive 2 months post-op
Murray et al [49] 1975 F/43 SLE 2 yes 4+ MVR Beall Surgitoul mechanical prosthesis alive 6 months post-op
Paget et al [50] 1975 F/18 SLE 4 yes 4+ MVR Porcine xenograft (bioprosthesis) alive 4 months post-op
Kinney et al [51] 1980 F/27 SLE 0.3 no 4+ MVR Hancock porcine bioprosthesis NR
Rawsthorne et al [52] 1981 M/51 SLE 21 no 4+ MVRc Hancock porcine bioprosthesis NR
Brennan et al
[53]
1983 F/20 SLE 2 yes 4+ MVR Björk-Shiley mechanical prosthesis CVA 17 months post-op
Rozman et al
[54]
1986 M/43 SLE 2 yes NR MVR Starr-Edwards mechanical prosthesis alive 4 years post-op
Moynihan et al
[55]
1988 F/54 SLE 2 yes 4+ MVRc Carpentier-Edwards porcine bioprosthesis alive 26 months post-op
Straaton et al
[56]
1988 F/22 SLE <1 no 4+ MVRd Carpentier-Edwards heterograft (bioprosthesis) NR
   F/67 SLE 10 yes 2+/3+ MVRc St. Jude mechanical prosthesis died intraoperatively
Ferraris et al
[57]
1990 M/34 SLE 9 yes 4+ MVR Carpentier-Edwards bioprosthesis alive 2.5 years post-op
Alvarez et al
[58]
1994 F/42 APS 1 no 2+/3+ MVR Medtronic Hall mechanical prosthesis NR
Kalangos et al
[40]
1995 F/28 SLE 0.5 yes 4+ MVP Resection of the prolapsed posterior commissure and restoration with an autologous pericardial patch; sliding plasty of the anterior leaflet; transposition of secondary chordae to the commisure; Carpentier- Edwards annuloplasty ring no MR recurrence 1 year post-op
Chauvaud et al [41] 1995 F/17 SLE 5 yes 4+ MVP Posterior leaflet enlargement with pericardial
patch and Carpentier-Edwards annuloplasty ring
MS 6 months post-op
due to calcification
        redo MVR Cryopreserved homograft alive 1 year post-op
Shahian et al
[59]
1995 F/29 APS 0 yes 4+ MVR St. Jude mechanical prosthesis alive 2 years post-op
Gordon et al
[46]
1996 M/37 SLE, APS >2 yes 1+/2+ MVRc Carpentier-Edwards porcine bioprosthesis recurrent A-V fistula
        redo MVR Carpentier-Edwards porcine bioprosthesis died 1 month post-op
Morin et al [33] 1996 F/40 SLE 12 yes 4+ MVR St. Jude mechanical prosthesis alive 2 weeks post-op
East et al [60] 2000 F/51 SLE, APS NR no 4+ MVRe not further specified NR
   F/49 SLE, APS 7 yes 4+ MVR not further specified NR
Hakim et al [42] 2001 F/23 SLE 8 yes 4+ MVR St. Jude mechanical prosthesis alive >1 year post-op
   F/54 SLE 7 yes 4+ MVPf not further specified MR 29 months post-op
        redo MVR St. Jude mechanical prosthesis alive >5 years post-op
   F/64 SLE 2 yes 4+ MVPe Quadrangular resection of the posterior leaflet and Duran annuloplasty ring alive >3 years post-op
Kato et al [43] 2001 F/52 APS NR no 4+ MVP Kay's annuloplasty and Cosgrove annuloplasty ring alive 3 months post-op
Mottram et al
[23]
2002 M/50 APS 0 no 0/1+ MVP Removal of two mitral valve masses alive 9 weeks post-op
da Silva et al
[47]
2003 F/54 SLE, APS 13 yes 4+ MVR Bioprosthesis (not further specified) bioprosth. thrombosis and death 9 months post-op
Schneider et al [44] 2003 M/23 SLE NR NR 4+ MVP not further specified NR
Georghiou et al [61] 2003 F/44 SLE 1 yes 3+ MVRc,d St. Jude mechanical prosthesis alive 6 months post-op
Bordin et al [62] 2003 F/57 SLE, APS 3 NR 4+ MVR Mechanical prosthesis (not further specified) MI 2 days post-op
Berkun et al
[63]
2004 F/48 APS NR yes 3+/4+ MVR Carbomedics mechanical prosthesis MR 90 months post-op
        redo MVR not further specified died 6 months post-op
   F/73 APS NR yes 3+/4+ MVR Hancock porcine bioprosthesis died 13 months post-op
   F/47 APS NR yes 3+/4+ MVRc Carbomedics mechanical prosthesis splenic embolus 3 and CVA 10 months post-op
alive 42 months post-op
   F/38 SLE, APS NR yes 3+/4+ MVR Carbomedics mechanical prosthesis alive 32 months post-op
   F/51 SLE, APS NR yes 3+/4+ MVR Carbomedics mechanical prosthesis alive 33 months post-op
Fernández et al [45] 2005 F/36 SLE 8 NR 4+ MVP not further specified mild MR 1 year post-op
Taguchi et al
[24]
2006 F/34 SLE 9 yes 0/1+ MVP Resection of A3 and attached chordae (en-bloc);
restoration of the anterior leaflet; 4 PTFE neochordae
no MR recurrence 6 months post-op
Einav et al [64] 2007 F/28 SLE, APS 4.5 yes 4+ MVRc,d Mechanical prosthesis (not further specified) NR
Takayama et al [16] 2008 M/58 SLE, APS 0 no 3+/4+ MVP Valvuloplasty and annuloplasty (not further specified) NR
Bouma et al 2010 M/49 SLE 1.5 yes 4+ MVP Quadrangular resection of the posterior stable trace MR leaflet (P2) and Carpentier-Edwards annuloplasty ring stable trace MR 11 years post-op
   M/56 SLE 4 yes 4+ MVR St. Jude mechanical prosthesis alive >1.5 years post-op
   F/28 APS 1 no 4+ MVR St. Jude mechanical prosthesis alive >1.5 years post-op
   F/22 APS 0.5 no 2+ MVP Quadrangular resection of the posterior leaflet (P2) and Cosgrove-Edwards annuloplasty ring no MR recurrence 1.5 years post-op
  1. A-V, atrioventricular; APS, antiphospholipid syndrome; CVA, cerebrovascular accident; F, female; M, male; MI, myocardial infarction; MR, mitral regurgitation; MS, mitral stenosis;MVP, mitral valve plasty; MVR, mitral valve repair; NR, not reported; PTFE, polytetrafluorethylene; SLE, systemic lupus erythematosus
  2. areports not written in English or reports of mitral valve surgery in patients with SLE and/or APS without a description of MR etiology and mitral valve pathology were excluded; cases of MS (n = 4) or combined MR/MS (n = 11) caused by Libman-Sacks endocarditis were also excluded
  3. bMR severity grading: 0, no or trace MR; 1+, mild MR; 2+, moderate MR; 3+, moderate-to-severe MR; 4+, severe MR
  4. cincluding aortic valve replacement (AVR)
  5. dincluding tricuspid valve plasty (TVP)
  6. eincluding CABG
  7. fincluding aortic valve plasty (AVP)
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