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Table 2 Chemical measurements, cellular characteristics, and survival as a function of pleural fluid appearance.

From: Does pleural fluid appearance really matter? The relationship between fluid appearance and cytology, cell counts, and chemical laboratory measurements in pleural effusions of patients with cancer

Characteristics

Pleural Fluid Color

 

Non-bloody

n = 206

Bloody

n = 159

p value

Primary malignancy, No. (%)

   

Lung

107 (51.9%)

70 (44.0%)

 

Breast

45 (21.8%)

31 (19.5%)

 

Gastrointestinal

11 (5.4%)

12 (7.5%)

 

Leukemia

6 (2.9%)

11 (6.9%)

 

Lymphoma

10 (4.9%)

6 (3.8%)

 

Other tumors

27 (13.1%)

29 (18.3%)

 

Previous thoracentesis

   

Mean (95% CI)

1.7 (1.6 - 1.9)

1.8 (1.7 - 1.9)

NS

Mean survival

   

Days (95%CI)

176.9 (141.2 - 212.6)

130.8 (101.0 - 160.6)

NS

Fluid chemistry, Mean (95%CI)

   

Glucose (mg/dl)

102.9 (96.6 - 109.2)

93.5 (86.5 - 100.4)

<0.05

Protein (g/dl)

3.8 (3.7 - 4.0)

4.1 (3.9 - 4.3)

NS

LDH (IU/dl)

863.4 (680.8 - 1046.1)

1913.6 (1454.1 - 2373.1)

<0.01

Cholesterol (mg/dl)

70.8 (66.3 - 75.3)

73.1 (67.8 - 78.4)

NS

Cellular characteristics, Mean (95%CI)

   

Mean WBC 103/μL

0.7 (0.6 - 0.9)

1.6 (0.9 - 2.3)

<0.01

Mean RBC 103/μL

12.3 (7.1 - 17.5)

220.5 (81.8 - 359.2)

<0.01

PMN cells (%)

15.0 (12.0 - 18.0)

20.5 (16.5 - 24.5)

<0.05

Mononuclear cells (%)

64.0 (60.0 - 68.0)

60.8 (56.3 - 65.3)

NS

Cytology, No. (%)

   

Positive

170 (82.5%)

131 (82.4%)

NS

Negative

36 (17.5%)

28 (17.6%)

NS