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Table 2 Summary of intra-operative variables stratified by post-operative CSA-AKI.

From: Difference between pre-operative and cardiopulmonary bypass mean arterial pressure is independently associated with early cardiac surgery-associated acute kidney injury

Variable No AKI (n = 92) AKI (n = 65) p-value
Valve only surgery (%) 26 (28.3) 12 (18.5) 0.16
Combined (valve + CABG) (%) 43 (46.7) 21 (32.3) 0.07
Re-operation (%) 8 (8.7) 6 (9.2) 0.91
# Grafts (mean [± SD]) 3.4 ± 1.1 3.5 ± 1.1 0.77
Duration of CPB (min, mean [± SD]) 126.6 ± 52 127.2 ± 63.2 0.69
Duration of cross clamp (min, mean [± SD]) 90.9 ± 46.9 88.7 ± 57.1 0.42
Average CPB MAP (mmHg, mean [± SD]) 57.8 ± 5.1 56.9 ± 4.9 0.25
Minutes <MAP 60 mmHg (median [± IQR]) 59 ± 65 56 ± 45 0.49
Minutes <MAP 50 mmHg (median [± IQR]) 2.5 ± 10 5.0 ± 15 0.35
Delta MAP (mmHg, mean [± SD]) 28.0 ± 13.2 31.3 ± 13.8 0.10
PRBC transfusions (units, mean [± SD]) 1.8 ± 1.5 2.4 ± 2.3 0.27
Patients transfused with PRBC (%) 23 (25) 19 (29.2) 0.56
Insulin dose (Units, mean [± SD]) 3.3 ± 1.3 3.6 ± 3.1 0.72
Furosemide dose (mg, n = 9, n = 7, mean [± SD]) 22.8 ± 10.3 27.1 ± 12.5 0.50
Ultrafiltration (mL, n = 34, n = 25, mean [± SD]) 1440 ± 1049 1470 ± 1344 0.98
Received tranexamic acid (%) 83 (90.2) 58 (89.2) 0.84
Received aprotinin (%) 0 (0) 0 (0) NS
Use of side-biting clamp (%) 16 (17.4) 21 (32.2) 0.03
Average flow (mL/kg/min, mean[± SD]) 60.9 ± 7.1 55.5 ± 8.4 0.001
Average temperature (°C, mean [± SD]) 35.3 ± 1.4 35.5 ± 1.1 0.75
  1. Abbreviations: AKI = acute kidney injury; CABG = coronary artery bypass graft, CPB = cardiopulmonary bypass; MAP = mean arterial pressure; PRBC = packed red blood cell