Table 2 Summary of intra-operative variables stratified by post-operative CSA-AKI.
Variable | No AKI (n = 92) | AKI (n = 65) | p-value |
|---|---|---|---|
Valve only surgery (%) | 26 (28.3) | 12 (18.5) | 0.16 |
Combined (valve + CABG) (%) | 43 (46.7) | 21 (32.3) | 0.07 |
Re-operation (%) | 8 (8.7) | 6 (9.2) | 0.91 |
# Grafts (mean [± SD]) | 3.4 ± 1.1 | 3.5 ± 1.1 | 0.77 |
Duration of CPB (min, mean [± SD]) | 126.6 ± 52 | 127.2 ± 63.2 | 0.69 |
Duration of cross clamp (min, mean [± SD]) | 90.9 ± 46.9 | 88.7 ± 57.1 | 0.42 |
Average CPB MAP (mmHg, mean [± SD]) | 57.8 ± 5.1 | 56.9 ± 4.9 | 0.25 |
Minutes <MAP 60 mmHg (median [± IQR]) | 59 ± 65 | 56 ± 45 | 0.49 |
Minutes <MAP 50 mmHg (median [± IQR]) | 2.5 ± 10 | 5.0 ± 15 | 0.35 |
Delta MAP (mmHg, mean [± SD]) | 28.0 ± 13.2 | 31.3 ± 13.8 | 0.10 |
PRBC transfusions (units, mean [± SD]) | 1.8 ± 1.5 | 2.4 ± 2.3 | 0.27 |
Patients transfused with PRBC (%) | 23 (25) | 19 (29.2) | 0.56 |
Insulin dose (Units, mean [± SD]) | 3.3 ± 1.3 | 3.6 ± 3.1 | 0.72 |
Furosemide dose (mg, n = 9, n = 7, mean [± SD]) | 22.8 ± 10.3 | 27.1 ± 12.5 | 0.50 |
Ultrafiltration (mL, n = 34, n = 25, mean [± SD]) | 1440 ± 1049 | 1470 ± 1344 | 0.98 |
Received tranexamic acid (%) | 83 (90.2) | 58 (89.2) | 0.84 |
Received aprotinin (%) | 0 (0) | 0 (0) | NS |
Use of side-biting clamp (%) | 16 (17.4) | 21 (32.2) | 0.03 |
Average flow (mL/kg/min, mean[± SD]) | 60.9 ± 7.1 | 55.5 ± 8.4 | 0.001 |
Average temperature (°C, mean [± SD]) | 35.3 ± 1.4 | 35.5 ± 1.1 | 0.75 |