Table 1 Baseline Characteristics of Patients, According to Treatment Group
From: Impact of aprotinin and renal function on mortality: a retrospective single center analysis
| Â | No Aprotinin Mean (SD) | Aprotinin Mean (SD) | p-value |
|---|---|---|---|
Age | 61.1 (12.7) | 64.5 (14.1) | 0.045 |
Height (cm) | 171.6 (8.9) | 171.6 (10.6) | 0.999 |
Weight (kg) | 91.1 (22.9) | 86.0 (20.5) | 0.062 |
Lowest HCT on bypass | 23.1 (4.8) | 21.6 (4.7) | 0.01 |
Blood glucose (on bypass) | 231.6 (61.6) | 245.8 (74.6) | 0.10 |
Blood glucose (48 hrs postoperative) | 202.1 (59.9) | 216.5 (80.01) | 0.11 |
CPB duration | 75.9 (56.9) | 113.8 (64.3) | < 0.001 |
RBC transfusion on bypass | 1.27 (1.92) | 2.13 (2.48) | Â |
Prime volume | 575.0 (205.2) | 588.6 (324.3) | 0.71 |
UOP on pump | 261.5 (241.9) | 287.3 (290.9) | 0.51 |
| Â | No Aprotinin No. (%) | Aprotinin No. (%) | p-value |
Male | 79 (68.1) | 94 (70.15) | 0.73 |
Mild renal failure | 45 (38.79) | 45 (33.33) | 0.55 |
Moderate renal failure | 39 (33.62) | 45 (33.33) | Â |
Severe renal failure | 32 (27.59) | 45 (33.33) | Â |
Diabetes | 49 (42.24) | 51 (38.06) | 0.50 |
COPD none | 100 (86.21) | 115 (85.19) | 0.69 |
COPD mild | 7 (6.0) | 7 (5.2) | Â |
COPD mod | 8 (6.9) | 9 (6.7) | Â |
COPD severe | 1 (0.9) | 4 (3.0) | Â |
Hypertension | 90 (77.6) | 110 (81.5) | 0.44 |
Diabetes | 49 (42.2) | 51 (38) | Â |
Peripheral vascular disease | 17 (14.7) | 28 (20.7) | 0.21 |
Myocardial infarction | 44 (37.9) | 52 (38.5) | 0.92 |
Congestive heart failure | 42 (36.2) | 83 (61.5) | < 0.001 |
One year mortality | 20 (17.2) | 43 (32.1) | 0.007 |