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Table 1 Baseline Characteristics of Patients, According to Treatment Group

From: Impact of aprotinin and renal function on mortality: a retrospective single center analysis

  No Aprotinin
Mean (SD)
Aprotinin
Mean (SD)
p-value
Age 61.1 (12.7) 64.5 (14.1) 0.045
Height (cm) 171.6 (8.9) 171.6 (10.6) 0.999
Weight (kg) 91.1 (22.9) 86.0 (20.5) 0.062
Lowest HCT on bypass 23.1 (4.8) 21.6 (4.7) 0.01
Blood glucose (on bypass) 231.6 (61.6) 245.8 (74.6) 0.10
Blood glucose
(48 hrs postoperative)
202.1 (59.9) 216.5 (80.01) 0.11
CPB duration 75.9 (56.9) 113.8 (64.3) < 0.001
RBC transfusion on bypass 1.27 (1.92) 2.13 (2.48)  
Prime volume 575.0 (205.2) 588.6 (324.3) 0.71
UOP on pump 261.5 (241.9) 287.3 (290.9) 0.51
  No Aprotinin
No. (%)
Aprotinin
No. (%)
p-value
Male 79 (68.1) 94 (70.15) 0.73
Mild renal failure 45 (38.79) 45 (33.33) 0.55
Moderate renal failure 39 (33.62) 45 (33.33)  
Severe renal failure 32 (27.59) 45 (33.33)  
Diabetes 49 (42.24) 51 (38.06) 0.50
COPD none 100 (86.21) 115 (85.19) 0.69
COPD mild 7 (6.0) 7 (5.2)  
COPD mod 8 (6.9) 9 (6.7)  
COPD severe 1 (0.9) 4 (3.0)  
Hypertension 90 (77.6) 110 (81.5) 0.44
Diabetes 49 (42.2) 51 (38)  
Peripheral vascular disease 17 (14.7) 28 (20.7) 0.21
Myocardial infarction 44 (37.9) 52 (38.5) 0.92
Congestive heart failure 42 (36.2) 83 (61.5) < 0.001
One year mortality 20 (17.2) 43 (32.1) 0.007
  1. COPD - chronic obstructive pulmonary disease; CPB - cardiopulmonary bypass; HCT - hematocrit; RBC - red blood cell; UOP - urine output