From: Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery
Study population (n = 220) | FVL 1691 G/G (n = 196) | FVL 1691 G/A (n = 24) | p value* | PT 20210 G/G (n = 212) | PT 20210 G/A (n = 8) | p value** | ACE I/I & I/D (n = 124) | ACE D/D (n = 57) | p value*** | |
---|---|---|---|---|---|---|---|---|---|---|
CPB time (min) | 77.5 ± 15.7 | 77.5 ± 15.7 | 77.3 ± 15.9 | NS | 77.5 ± 15.9 | 77.5 ± 9.0 | NS | 79.2 ± 17.5 | 75.2 ± 11.5 | NS |
Number of coronary grafts | 3.0 ± 1.1 | 3.0 ± 1.1 | 3.0 ± 0.9 | NS | 3.0 ± 1.1 | 2.4 ± 0.9 | NS | 3.1 ± 1.1 | 2.9 ± 1.0 | NS |
Postoperative blood loss at 24 hours, mL | 463.5 ± 155.1 | 487.1 ± 150.5 | 460.6 ± 155.7 | NS | 459.6 ± 133.6 | 566.9 ± 449.0 | NS | 448.5 ± 136.0 | 470.9 ± 130.5 | NS |
Total drainage, mL | 604.3 ± 204.1 | 597.4 ± 191.5 | 660.4 ± 286.3 | NS | 599.6 ± 176.5 | 730.0 ± 587.9 | NS | 581.1 ± 179.8 | 631.9 ± 187.4 | 0.045 |
Stay in intensive care unit, hours | 54.9 ± 80.4 | 56.6 ± 85.0 | 42.0 ± 9.1 | NS | 52.9 ± 73.4 | 109.6 ± 190.3 | NS | 56.3 ± 82.7 | 53.0 ± 60.4 | NS |
In-hospital Mortality, % | 6 (2.7) | 6 (3.1) | 0 | NS | 5 (2.4) | 1 (12.5) | NS | 3 (2.4) | 2 (3.5) | NS |