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Table 6 Univariate logistic regression analysis of the association of various factors with development of infection.

From: Are there independent predisposing factors for postoperative infections following open heart surgery?

Examined factors With
infection
n = 24
Without infection
n = 148
p Value
Co-morbidities    
Diabetes mellitus* 13 (22%) 46 (78%) 0.031
Arterial hypertension 18 (15.3%) 100 (84.7%) 0.469
COPD 4 (18.2%) 18 (81.8%) 0.542
Chronic renal failure 5 (45.5%) 6 (54.5%) 0.127
Peripheral vascular disease 5 (21.7%) 18 (78.3%) 0.253
Stroke 5 (26.3%) 14 (73.7%) 0.109
Unstable angina 6 (17.1%) 29 (82.9%) 0.543
Recent myocardial infarction 5 (10.9%) 41 (89.1%) 0.483
Older myocardial infarction 6 (19.4%) 25 (80.6%) 0.341
Pulmonary hypertension 1 (50%) 1 (50%) 0.195
Hyperlipidemia 7 (15.6%) 38 (84.4%) 0.718
Smoking 13 (18.8%) 56 (81.2%) 0.135
Alcohol abuse 1 (7.7%) 12 (92.3%) 0.506
Intraoperative factors    
Duration of anesthesia (hours) 6.78 ± 1.94 6.28 ± 1.65 0.181
Extra-corporeal circulation (min) 138.87 ± 85.88 119.27 ± 72.67 0.234
Ischemia time (min) 101,75 ± 61,76 88,95 ± 58,19 0.322
Degree of hypothermia (°C) 23.33 ± 12.40 25.40 ± 11.38 0.416
Emergency operation 5 (45.5%) 6 (54.5%) 0.545
Postoperative factors    
Intra-aortic balloon pump (IABP) 5 (27.8%) 13 (72.2%) 0.069
Duration of mechanical ventilation* 5.42 ± 10.31 1.34 ± 1.35 0.014
Re-intubation 11 (50%) 11 (50%) 0.337
Tracheotomy 7 (87.5%) 1 (12.5%) 0.133
Enteral nutrition for >10 days 5 (100%) 0 0.999
Parenteral nutrition for >10 days 6 (100%) 0 0.328
Re-operation 7 (53.8%) 6 (46.2%) 0.310
Complications in the CVICU* 19 (43.2%) 25 (56.8%) 0.000
Re-admission to the CVICU* 12 (60%) 8 (40%) 0.000
Total CVICU length of stay 12.54 ± 12.60 2.84 ± 2.60 0.519
CVICU length of stay >15 days 8 (80%) 2 (20%) 0.519
Perioperative transfusions    
N of RBC units transfused 6.79 ± 4.45 3.97 ± 2.35 0.000
N of FFP units transfused 7.00 ± 6.39 3.93 ± 2.96 0.002
N of PLT units transfused 8.13 ± 7.45 5.49 ± 4.57 0.026
  1. *Variables significantly associated with infection (p value < 0.05).
  2. COPD: Chronic obstructive pulmonary disease; CVICU: cardio-vascular intensive care unit