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Table 6 Univariate logistic regression analysis of the association of various factors with development of infection.

From: Are there independent predisposing factors for postoperative infections following open heart surgery?

Examined factors

With

infection

n = 24

Without infection

n = 148

p Value

Co-morbidities

   

Diabetes mellitus*

13 (22%)

46 (78%)

0.031

Arterial hypertension

18 (15.3%)

100 (84.7%)

0.469

COPD

4 (18.2%)

18 (81.8%)

0.542

Chronic renal failure

5 (45.5%)

6 (54.5%)

0.127

Peripheral vascular disease

5 (21.7%)

18 (78.3%)

0.253

Stroke

5 (26.3%)

14 (73.7%)

0.109

Unstable angina

6 (17.1%)

29 (82.9%)

0.543

Recent myocardial infarction

5 (10.9%)

41 (89.1%)

0.483

Older myocardial infarction

6 (19.4%)

25 (80.6%)

0.341

Pulmonary hypertension

1 (50%)

1 (50%)

0.195

Hyperlipidemia

7 (15.6%)

38 (84.4%)

0.718

Smoking

13 (18.8%)

56 (81.2%)

0.135

Alcohol abuse

1 (7.7%)

12 (92.3%)

0.506

Intraoperative factors

   

Duration of anesthesia (hours)

6.78 ± 1.94

6.28 ± 1.65

0.181

Extra-corporeal circulation (min)

138.87 ± 85.88

119.27 ± 72.67

0.234

Ischemia time (min)

101,75 ± 61,76

88,95 ± 58,19

0.322

Degree of hypothermia (°C)

23.33 ± 12.40

25.40 ± 11.38

0.416

Emergency operation

5 (45.5%)

6 (54.5%)

0.545

Postoperative factors

   

Intra-aortic balloon pump (IABP)

5 (27.8%)

13 (72.2%)

0.069

Duration of mechanical ventilation*

5.42 ± 10.31

1.34 ± 1.35

0.014

Re-intubation

11 (50%)

11 (50%)

0.337

Tracheotomy

7 (87.5%)

1 (12.5%)

0.133

Enteral nutrition for >10 days

5 (100%)

0

0.999

Parenteral nutrition for >10 days

6 (100%)

0

0.328

Re-operation

7 (53.8%)

6 (46.2%)

0.310

Complications in the CVICU*

19 (43.2%)

25 (56.8%)

0.000

Re-admission to the CVICU*

12 (60%)

8 (40%)

0.000

Total CVICU length of stay

12.54 ± 12.60

2.84 ± 2.60

0.519

CVICU length of stay >15 days

8 (80%)

2 (20%)

0.519

Perioperative transfusions

   

N of RBC units transfused

6.79 ± 4.45

3.97 ± 2.35

0.000

N of FFP units transfused

7.00 ± 6.39

3.93 ± 2.96

0.002

N of PLT units transfused

8.13 ± 7.45

5.49 ± 4.57

0.026

  1. *Variables significantly associated with infection (p value < 0.05).
  2. COPD: Chronic obstructive pulmonary disease; CVICU: cardio-vascular intensive care unit