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Table 1 Table of included RCTs

From: The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis

  

Subjects (n)

Glucose ranges

Early Mortality

AF

Pacing

Time in ICU*

Time on Ventilation

Author (year)

Control Period

Total (non-DM/DM)

Tight/normal control

mg/dL

n(%)

p

n (%)

p

n (%)

p

Mean ± SD

p

Mean ± SD

p

    

Control

Tight

Control

Tight

 

Control

Tight

 

Control

Tight

 

Control

Tight

 

Control

Tight

 

Ingels [15] (2006)

Post

970 (N/A)

477/493

< 220

< 110

37%

16%

0.005

N/A

N/A

--

N/A

N/A

--

N/A

N/A

--

N/A

N/A

--

Chaney [12]

(1999)

Peri

20 (20/0)

10/10

-

100 - 150

N/A

N/A

--

2 (20%)

4 (40%)

N/A

N/A

N/A

--

N/A

N/A

--

N/A

N/A

--

Gandhi [13]

(2007)

Peri

400 (327/73)

185/186

< 200

< 100

N/A

N/A

--

59 (32%)

54 (29%)

n.s.

N/A

N/A

--

N/A

N/A

--

N/A

N/A

--

Hoedemaekers

[14] (2005)

Post

20 (20/0)

10/10

< 200

80 - 110

N/A

N/A

--

N/A

N/A

--

N/A

N/A

--

20.3 ± 2.5

22.1 ± 1.8

0.09

9.8 ± 4.6

11.2 ± 6.6

n.s.

Groban [16]

(2002)

Peri/Post

381 (381/0)

188/193

-

80 - 120

0%

1.60%

n.s.

68 (35%)

60 (32%)

n.s.

2 (1%)

3 (2%)

n.s.

N/A

N/A

--

32 ± 4.0

31 ± 4.0

N/A

Koskenkari [17]

(2005)

Peri

40 (40/0)

20/20

< 180

108 - 180

N/A

N/A

--

14 (70%)

12 (60%)

N/A

12 (60%)

3 (15%)

0.008

48 ± 28.8

76.8 ± 112.8

0.8

12.9 ± 14.2

11.4 ± 20.1

0.1

Lazar [18]

(2004)

Peri

141 (N/A)

72/69

< 250

125 - 200

0%

0%

n.s.

29 (42%)

12 16.6%

0.002

27 (39%)

10 13.8%

0.001

32.8 +2.6

17.3 +1.0

0.001

10.7 ± 0.6

6.9 ± 0.3

< .001

  1. This table describes the seven RCTs that met our inclusion/exclusion criteria and were included in the meta-analysis. In the table, "peri" and "post" designate the timing of glycaemic control as either during surgery (peri) or after surgery (post). One study, Groban et al, maintained tight glycaemic control both during and after surgery. "DM" = diabetes mellitus (not specified if this was Type I or Type II). The glucose ranges for the "tight" control and "normal" control groups are given. Where no glucose range is listed in the "normal" ranges indicates that no attempt was made to keep the patients under any glycaemic control. The number of cases (n%) or the mean ± SD for each of the five outcome measures is listed for each study. Not every RCT included provided data on each of the outcome measures, thus some boxes are blank or listed as "N/A" (not available). Where provided, the p-value for the statistical comparison within that study is also listed in the table.