Table 1 ACT, APTT and INR values Peri and Post-operatively; Also blood loss, Hb concentration and blood product use peri-operatively, is reported
From: Lepirudin as an alternative to "heparin allergy" during cardiopulmonary bypass
Time (Hours) | ACT (sec) | APTT (sec) | INR | Blood loss (ml) | Hg (mg/dl) | Blood products |
|---|---|---|---|---|---|---|
Operating Theatre | Â | Â | Â | Â | Â | Â |
10:15 am ( Pre-op) | 132 | 29.4 | 1.3 | 140 | 12.0 | Â |
11:00 (post-lepirudin) | >1300 | >200 | 10.0 | Â | Â | Â |
11:25 (pre-CPB) | >1500 | 120 | 1.9 | Â | Â | Â |
11:43 (CPB+5 mins) | >1000 | >250 | >10 | Â | Â | Â |
12:00 (+20 min) | >1000 | >250 | >10 | Â | Â | Â |
12:15 pm (+35 min) | >1000 | >250 | >10 | Â | Â | Â |
12:30 (+50 min) | 436 | 130 | 6.6 | Â | Â | Â |
12:45 ( off CPB) | 478 | 111 | 3.0 | Â | Â | Â |
13:15 (+30 min post-CPB) | 476 | 73 | 1.9 | 230 | 7.0 | NONE |
ITU | Â | Â | Â | Â | Â | Â |
14:10 | Â | 54 | 1.5 | 140 | 8.9 | Â |
15:00 | Â | 38 | 1.3 | 40 | 7.7 | Â |
16:15 | Â | 47 | 1.7 | 30 | 8.9 | RCC:2, FFPs:2 |
17:00 | Â | 51 | 1.5 | 40 | 7.5 | RCC:2 |
18:50 | Â | 40 | 1.3 | 3000 | 6.7 | PLTs:2 FFPs:2 |
20:50 | Â | 44 | 1.3 | 1800 | 5.9 | RCC:6 PLTs:2 CryoP:4 FFPs:2 |
Day 1 | Â | Â | Â | Â | Â | Â |
16:00 | Â | 34 | 1.2 | 200 | 8.9 | NONE |
18:00 | Â | 38 | 1.3 | 40 | 9.0 | Â |