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Table 1 dose of colchicine in pericardial effusion

From: Recurrent pericardial effusion after cardiac surgery: the use of colchicine after recalcitrant conventional therapy

Autors Loading Dose Maintenance Journal and year NSAIDs or Corticosteroids
Horneffer PJ et al. 2 mg/day for 1 or 2 days 1 mg/day for several weeks or months J Thor Cardiov Surgery 1990 and ESC 2004  
Imazio et al. 1 or 2 mg/day (0.5 or 1 mg/day < 70 kg) 0.5 or 1.0 mg/day for 3 months Circulation 2005 Aspirin 800 mg every 6 or 8 hours for 7 or 10 days (tapering for 3-4 weeks)
Spodick DH
(Permayner-Miranda)
0.6 mg twice daily 0.6 mg twice daily for 1 or 2 weeks and tapering for 1 or 2 weeks JAMA 2003 Ibuprofen 800 mg every 8 hours
Millaire A et Al 3 mg/day 1 mg/day (1 to 27 months -mean 7.7) Eur Heart J 1994  
Guindo J et Al 1 mg/day 1 mg/day Circulation 1990 Prednisone 20-60 mg/day
Lange RA 0.6 mg twice daily 0.6 mg twice daily NEJM 2004 Aspirin 2-4 mg/daily or Indometacin 75-225 mg/daily or Ibuprofene 1600-3200 mg/daily
Adler Y et Al 1 mg/day 1 mg/day Am J Cardiol 1994  
De la Serna R et al 1 mg/day 1 mg/day Lancet 1987  
Adler Y et Al.   1 mg/day (1 or 6
months)
Clin Cardiol 1998 Aspirin
Adler Y et Al. 2-3 mg/day (unclear) 1 mg/day at least 1 year Circulation 1998 Ibuprofen
Imazio M et Al.
CORE
1.0-2.0 mg/day 0.5-1.0 mg/day for 6 months Arch Intern Med 2005 Aspirin 800 mg every 6 or 8 hours for 7 or 10 days (tapering for 3-4 weeks)
Maisch B et Al. 2 mg/day 1 mg/day Eur Heart J 2004  
Shabetai R 2 mg/day 1 mg/day   
Soler-Soler J et Al 2 mg/day 1 mg/day Heart 2004  
Imazio M et Al.
COPPS (Prevention PPS)
1.0-2.0 mg/day first day (1 mg/d < 70 kg) 0.5-1.0 mg/day for 1 month (0.5 mg/d < 70 kg) Int J Cardiology 2006  
Little and Freeman 2 mg/day 1 mg/day for 3 months Circulation 2006 Aspirin 650-975 mg every 6-8 h for 4 weeks
Imazio et Al. 1 mg/day 1 mg/day Eur Heart Journal 2003 Aspirin 600-800 mg every 6 or 8 hours for 7 or 10 days (tapering for 2-3 weeks)
Sagristà-Sauleda et Al 1-2 mg 0.5-1 mg/day for 1 year Rev Esp Cardiol 2005  
Finkelstein et Al. (Prevention PPS)   1.5 mg every 8 h/day for 1 month Herz 2002  
Imazio et Al. 2 mg 1 mg/day for 6-12 months J Cardiov Medicine 2007  
Artom et Al. 1 mg 1 mg Eu Heart Journal 2005