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Table 1 dose of colchicine in pericardial effusion

From: Recurrent pericardial effusion after cardiac surgery: the use of colchicine after recalcitrant conventional therapy

Autors

Loading Dose

Maintenance

Journal and year

NSAIDs or Corticosteroids

Horneffer PJ et al.

2 mg/day for 1 or 2 days

1 mg/day for several weeks or months

J Thor Cardiov Surgery 1990 and ESC 2004

 

Imazio et al.

1 or 2 mg/day (0.5 or 1 mg/day < 70 kg)

0.5 or 1.0 mg/day for 3 months

Circulation 2005

Aspirin 800 mg every 6 or 8 hours for 7 or 10 days (tapering for 3-4 weeks)

Spodick DH

(Permayner-Miranda)

0.6 mg twice daily

0.6 mg twice daily for 1 or 2 weeks and tapering for 1 or 2 weeks

JAMA 2003

Ibuprofen 800 mg every 8 hours

Millaire A et Al

3 mg/day

1 mg/day (1 to 27 months -mean 7.7)

Eur Heart J 1994

 

Guindo J et Al

1 mg/day

1 mg/day

Circulation 1990

Prednisone 20-60 mg/day

Lange RA

0.6 mg twice daily

0.6 mg twice daily

NEJM 2004

Aspirin 2-4 mg/daily or Indometacin 75-225 mg/daily or Ibuprofene 1600-3200 mg/daily

Adler Y et Al

1 mg/day

1 mg/day

Am J Cardiol 1994

 

De la Serna R et al

1 mg/day

1 mg/day

Lancet 1987

 

Adler Y et Al.

 

1 mg/day (1 or 6

months)

Clin Cardiol 1998

Aspirin

Adler Y et Al.

2-3 mg/day (unclear)

1 mg/day at least 1 year

Circulation 1998

Ibuprofen

Imazio M et Al.

CORE

1.0-2.0 mg/day

0.5-1.0 mg/day for 6 months

Arch Intern Med 2005

Aspirin 800 mg every 6 or 8 hours for 7 or 10 days (tapering for 3-4 weeks)

Maisch B et Al.

2 mg/day

1 mg/day

Eur Heart J 2004

 

Shabetai R

2 mg/day

1 mg/day

  

Soler-Soler J et Al

2 mg/day

1 mg/day

Heart 2004

 

Imazio M et Al.

COPPS (Prevention PPS)

1.0-2.0 mg/day first day (1 mg/d < 70 kg)

0.5-1.0 mg/day for 1 month (0.5 mg/d < 70 kg)

Int J Cardiology 2006

 

Little and Freeman

2 mg/day

1 mg/day for 3 months

Circulation 2006

Aspirin 650-975 mg every 6-8 h for 4 weeks

Imazio et Al.

1 mg/day

1 mg/day

Eur Heart Journal 2003

Aspirin 600-800 mg every 6 or 8 hours for 7 or 10 days (tapering for 2-3 weeks)

Sagristà-Sauleda et Al

1-2 mg

0.5-1 mg/day for 1 year

Rev Esp Cardiol 2005

 

Finkelstein et Al. (Prevention PPS)

 

1.5 mg every 8 h/day for 1 month

Herz 2002

 

Imazio et Al.

2 mg

1 mg/day for 6-12 months

J Cardiov Medicine 2007

 

Artom et Al.

1 mg

1 mg

Eu Heart Journal 2005