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Table 3 Perioperative patients’ characteristics within first 24 hours

From: Hemodynamic effects of peri-operative statin therapy in on-pump cardiac surgery patients

Variable Statin No-Statin p-value
(n = 276) (n = 202)  
Laboratory findings    
 Creatinine serum max. (mg/dl) 1.9 ± 1.25 2.0 ± 3.8 0.58
 Increased in serum creatinine (%) 72 ± 116 76 ± 193 0.78
 Creatinine clearance min. (ml/min) 57 ± 32 56 ± 31 087
 Decreased creatinine clearance (ml/min) 18 ± 34 20 ± 42 0.72
 Hematocrit min. (%) 27 ± 4 27 ± 4 0.83
 Urea max. (mg/dl) 39 ± 26 42 ± 57 0.44
 Furosemide mean (mg/d) 96 ± 158 79 ± 100 019
 S-CPK (U/L) 973 ± 990 1139 ± 2559 0.37
 S-CPK-MB (U/L) 45 ± 45 50 ± 77 0.42
 Potassium (mmol/L) 4.5 ± 0.5 4.5 ± 0.5 0.48
 Lactate (mmol/L) 1.6 ± 1.4 1.6 ± 1.9 0.64
 Renal replacement therapy during hospital stay (%) 9.1 8.9 0.95
 Leucocytes (103/μl) 15 ± 7 14 ± 8 0.0001
Scores    
 Rifle Score (1st POD) (n = 285 / 59,6%)    
  R (risk) n = 60 32 28 0.72
  I (injury) n = 65 39 26  
  F (failure) n = 160 88 72  
 APACHE II Score 15 ± 6 15 ± 7 0.66
 SAPS II Score 25 ± 7 25 ± 8 0.61
Inotropes    
 Epinephrine (mg/d) 9 ± 123 2 ± 8 0.40
 Norepinephrine (mg/d) 2 ± 16 1 ± 6 0.24
 Enoximone (mg/d) 20 ± 114 22 ± 195 0.88
 Dobutamine (mg/d) 9 ± 44 13 ± 69 0.49
Other agents    
 Nitroglycerine (mg/d) 12 ± 32 9 ± 21 0.40
 Amiodarone (mg/d) 68 ± 286 60 ± 255 0.73
 Cortisone (mg/d) 21 ± 119 66 ± 449 0.11
Operative characteristics    
 Cross-clamp time (min) 94 ± 36 94 ± 41 0.90
 Cardiopulmonary bypass time (min) 147 ± 60 140 ± 78 0.30
  1. APACHE Acute Physiology and Chronic Health Evaluation II Score, SAPS: Simplified Acute Physiology Score, S-CPK Serum creatinine phosphokinase.