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Table 1 Univariate analysis of continuous parameters within the evaluation group.

From: Predicting restoration of kidney function during CRRT-free intervals

 

Outcome of CRRT-free interval

p-value

 

Recovery of kidney function

N = 103

Resumption of CRRT

N = 122

 

General Data

   

Age (years)

70 (IQR: 65-77)

74 (IQR: 61-78)

0.662

SOFA score

8.3 (SD: 3.62)

9.2 (SD: 3.78)

0.0421

Number of CRRT cycles

1 (IQR: 1-1.75)

2 (IQR: 1-4)

< 0.00012

Fluid balance

(during the last 12 h of CRRT)

   

Total balance (ml)

-315 (IQR: -807 to 214)

-336 (IQR: -1148 to 314)

0.742

Urine output (ml/h)

33 (IQR: 14.2-54.2)

8 (IQR: 0-20)

< 0.00012

Infused synthetic colloids (ml)

0 (IQR: 0-0)

0 (IQR: 0-0)

0.612

Fluid balance

(first 8 h after end of CRRT)

   

Total balance (ml)

443 (IQR: 43-1133)

909 (IQR: 502-1361)

0.00032

Urine output (ml/h)

66 (IQR: 29-122)

10 (IQR: 0-29)

< 0.00012

Infused synthetic colloids (ml)

0 (IQR: 0-0)

0 (IQR: 0-0)

0.462

Inotropes and vasoactive drugs

(8 h-maximum after end of CRRT)

   

Norepinephrine (μg/min)

0 (IQR: 0-0)

0 (IQR: 0-0)

0.282

Epinephrine (μg/min)

0 (IQR: 0-0)

0 (IQR: 0-0)

0.352

Dobutamine (μg/kg/min)

0 (IQR: 0-0)

0 (IQR: 0-0)

0.452

Hemodynamics

(Averaged 8 h after end of CRRT)

   

Mean arterial pressure (mmHg)

77 (IQR: 71-84)

73 (IQR: 67-80)

0.0132

Central venous pressure (mmHg)

11.2 (IQR: 8.6-15.3)

12.8 (IQR: 10.0-16.1)

0.0492

Heart rate (1/min)

86 (IQR: 77-94)

89 (IQR: 81-96)

0.0532

Laboratory values

(first value after end of CRRT)

   

Na+ (mmol/l)

139.9 (SD: 3.1)

139.6 (SD: 3.0)

0.491

K+ (mmol/l)

4.65 (IQR: 4.44-4.91)

4.70 (IQR: 4.40-4.90)

0.582

Creatinine (mg/dl)

1.90 (IQR: 1.50-2.60)

2.05 (IQR: 1.40-2.70)

0.982

Urea (mg/dl)

52.4 (SD: 17.7)

52.9 (SD: 19.6)

0.831

pH

7.45 (IQR: 7.42-7.48)

7.44 (IQR: 7.40-7.47)

0.0182

Standard bicarbonate (mmol/l)

26.4 (IQR: 24.4-28.6)

26.0 (IQR: 24.2-27.7)

0.172

Hemoglobin (mg/dl)

9.8 (IQR: 9.2-10.6)

9.4 (IQR: 8.7-10.4)

0.0142

Furosemide

(first 8 h after end of CRRT)

   

Total i.v. dose (mg)

50 (IQR: 0-100)

0 (IQR: 0-0)

< 0.00012

  1. Normally distributed data were analyzed with the t-test for independent samples (1), not-normally distributed data with the Mann-Whitney-test (2).