|
Variable
|
VAC therapy
|
Conventional treatment
|
p value
|
|---|
|
n
|
%
|
n
|
%
|
|---|
|
Number of patients
|
47
|
52.2
|
43
|
47.8
| |
|
Sex
|
|
Male
|
12
|
25.3
|
21
|
48.8
|
0.003**
|
|
Female
|
35
|
74.7
|
22
|
51.2
|
0.003**
|
|
Surgical procedure
|
|
Isolated or combined CABG procedure
|
32
|
68.1
|
29
|
67.4
|
0.262
|
|
Isolated valvular procedure
|
15
|
31.9
|
14
|
32.6
|
0.302
|
|
Diabetes mellitus
|
15
|
31.9
|
14
|
32.6
|
0.255
|
|
Obesity (BMI ≥ 30)
|
33
|
70.2
|
22
|
51.2
|
0.043**
|
|
LVEF ≤ 0.30
|
10
|
21.3
|
11
|
25.6
|
0.116
|
|
NYHA Class III–IV
|
19
|
40.4
|
13
|
30.2
|
0.078
|
|
COPD
|
9
|
19.1
|
8
|
18.6
|
0.298
|
|
Age > 65 years
|
26
|
55.3
|
13
|
30.2
|
0.004**
|
|
Renal failure*
|
2
|
4.3
|
1
|
2.3
|
0.065
|
|
Emergency surgery
|
7
|
14.9
|
5
|
11.6
|
0.122
|
|
Re-do surgery
|
4
|
8.5
|
3
|
6.9
|
0.190
|
|
Re-exploration
|
9
|
19.1
|
5
|
11.6
|
0.053
|
|
Post perfusion syndrome
|
13
|
27.7
|
10
|
23.2
|
0.272
|
|
Prolonged mechanical ventilation
|
21
|
44.7
|
16
|
37.2
|
0.185
|
|
ICU stay > 2 days
|
19
|
40.4
|
20
|
46.5
|
0.197
|
|
Prolonged use of inotropic drugs
|
20
|
42.6
|
17
|
39.5
|
0.177
|
|
Immunosuppression
|
1
|
2.1
|
1
|
2.3
|
0.344
|
| |
Mean
|
SD
|
Mean
|
SD
| |
|
CPB time (minutes)
|
119
|
33.18
|
123.1
|
28.28
|
0.150
|
|
X-clamp time (minutes)
|
98.2
|
28.08
|
99.3
|
14.14
|
0.313
|
|
Age (y)
|
67.96
|
10.47
|
57.3
|
14.7
|
0.004**
|
|
EuroSCORE
|
7.5
|
3.4
|
5.0
|
2.6
|
<0.001**
|
- *Serum creatinin >1.3 mg/dl.
- ** < 0.05 is the statistically significance value.
-
VAC = Vacuum-assisted closure; CABG = Coronary artery bypass graft; BMI = body mass index; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association; COPD = chronic obstructive pulmonary disease; CPB = cardiopulmonary bypass.
- The sum of percentages exceeds 100% because of rounding-off errors.
