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Table 2 Patients characteristics

From: Treatment outcomes of postoperative mediastinitis in cardiac surgery; negative pressure wound therapy versus conventional treatment

Variable VAC therapy Conventional treatment p value
n % n %
Number of patients 47 52.2 43 47.8  
Sex
 Male 12 25.3 21 48.8 0.003**
 Female 35 74.7 22 51.2 0.003**
Surgical procedure
 Isolated or combined CABG procedure 32 68.1 29 67.4 0.262
 Isolated valvular procedure 15 31.9 14 32.6 0.302
Diabetes mellitus 15 31.9 14 32.6 0.255
Obesity (BMI ≥ 30) 33 70.2 22 51.2 0.043**
LVEF ≤ 0.30 10 21.3 11 25.6 0.116
NYHA Class III–IV 19 40.4 13 30.2 0.078
COPD 9 19.1 8 18.6 0.298
Age > 65 years 26 55.3 13 30.2 0.004**
Renal failure* 2 4.3 1 2.3 0.065
Emergency surgery 7 14.9 5 11.6 0.122
Re-do surgery 4 8.5 3 6.9 0.190
Re-exploration 9 19.1 5 11.6 0.053
Post perfusion syndrome 13 27.7 10 23.2 0.272
Prolonged mechanical ventilation 21 44.7 16 37.2 0.185
ICU stay > 2 days 19 40.4 20 46.5 0.197
Prolonged use of inotropic drugs 20 42.6 17 39.5 0.177
Immunosuppression 1 2.1 1 2.3 0.344
  Mean SD Mean SD  
CPB time (minutes) 119 33.18 123.1 28.28 0.150
X-clamp time (minutes) 98.2 28.08 99.3 14.14 0.313
Age (y) 67.96 10.47 57.3 14.7 0.004**
EuroSCORE 7.5 3.4 5.0 2.6 <0.001**
  1. *Serum creatinin >1.3 mg/dl.
  2. ** < 0.05 is the statistically significance value.
  3. VAC = Vacuum-assisted closure; CABG = Coronary artery bypass graft; BMI = body mass index; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association; COPD = chronic obstructive pulmonary disease; CPB = cardiopulmonary bypass.
  4. The sum of percentages exceeds 100% because of rounding-off errors.
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