Treatment outcomes of postoperative mediastinitis in cardiac surgery; negative pressure wound therapy versus conventional treatment

Table 2 Patients characteristics

Variable	VAC therapy		Conventional treatment		p value
Variable	n	%	n	%	p value
Number of patients	47	52.2	43	47.8
Sex
Male	12	25.3	21	48.8	0.003**
Female	35	74.7	22	51.2	0.003**
Surgical procedure
Isolated or combined CABG procedure	32	68.1	29	67.4	0.262
Isolated valvular procedure	15	31.9	14	32.6	0.302
Diabetes mellitus	15	31.9	14	32.6	0.255
Obesity (BMI ≥ 30)	33	70.2	22	51.2	0.043**
LVEF ≤ 0.30	10	21.3	11	25.6	0.116
NYHA Class III–IV	19	40.4	13	30.2	0.078
COPD	9	19.1	8	18.6	0.298
Age > 65 years	26	55.3	13	30.2	0.004**
Renal failure*	2	4.3	1	2.3	0.065
Emergency surgery	7	14.9	5	11.6	0.122
Re-do surgery	4	8.5	3	6.9	0.190
Re-exploration	9	19.1	5	11.6	0.053
Post perfusion syndrome	13	27.7	10	23.2	0.272
Prolonged mechanical ventilation	21	44.7	16	37.2	0.185
ICU stay > 2 days	19	40.4	20	46.5	0.197
Prolonged use of inotropic drugs	20	42.6	17	39.5	0.177
Immunosuppression	1	2.1	1	2.3	0.344
	Mean	SD	Mean	SD
CPB time (minutes)	119	33.18	123.1	28.28	0.150
X-clamp time (minutes)	98.2	28.08	99.3	14.14	0.313
Age (y)	67.96	10.47	57.3	14.7	0.004**
EuroSCORE	7.5	3.4	5.0	2.6	<0.001**

*Serum creatinin >1.3 mg/dl.
** < 0.05 is the statistically significance value.
VAC = Vacuum-assisted closure; CABG = Coronary artery bypass graft; BMI = body mass index; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association; COPD = chronic obstructive pulmonary disease; CPB = cardiopulmonary bypass.
The sum of percentages exceeds 100% because of rounding-off errors.

ISSN: 1749-8090