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Table 2 Predictors of OS according to univariate analysis

From: Prognostic significance of postoperative serum carcinoembryonic antigen levels in patients with completely resected pathological-stage I non-small cell lung cancer

Risk factors

Favorable

Unfavorable

p Valuea

Age

≤70 y

>70 y

0.008

Gender

Female

Male

0.12

Smoking history

<5 PY

≥5 PY

0.088

ECOG PS

0

1

0.007

Serum CEA

NN group

HN group

0.043

HN group

HH group

0.062

Serum CYFRA

≤3.5 ng/mL

>3.5 ng/mL

0.90

Location

Left

Right

0.99

Surgical procedure

Major resection b

Sublobar resection

0.57

Tumor diameter

≤30 mm

>30 mm

< 0.001

Histology

Adeno

Others

0.070

VPI

Absent

Present

0.001

ALI

Absent

Present

0.008

Differentiation

Well

Moderate/Poor

0.037

  1. OS, Overall survival; PY, Pack-years; ECOG PS, European cooperative oncology group performance status; CEA, Carcinoembryonic antigen; CYFRA, Cytokeratin 19 fragment level; VPI, Visceral pleural invasion; ALI, Angiolymphatic invasion.
  2. a the log-rank test.
  3. b Major resection refers to lobectomy or pneumonectomy.