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Table 2 Predictors of OS according to univariate analysis

From: Prognostic significance of postoperative serum carcinoembryonic antigen levels in patients with completely resected pathological-stage I non-small cell lung cancer

Risk factors Favorable Unfavorable p Valuea
Age ≤70 y >70 y 0.008
Gender Female Male 0.12
Smoking history <5 PY ≥5 PY 0.088
ECOG PS 0 1 0.007
Serum CEA NN group HN group 0.043
HN group HH group 0.062
Serum CYFRA ≤3.5 ng/mL >3.5 ng/mL 0.90
Location Left Right 0.99
Surgical procedure Major resection b Sublobar resection 0.57
Tumor diameter ≤30 mm >30 mm < 0.001
Histology Adeno Others 0.070
VPI Absent Present 0.001
ALI Absent Present 0.008
Differentiation Well Moderate/Poor 0.037
  1. OS, Overall survival; PY, Pack-years; ECOG PS, European cooperative oncology group performance status; CEA, Carcinoembryonic antigen; CYFRA, Cytokeratin 19 fragment level; VPI, Visceral pleural invasion; ALI, Angiolymphatic invasion.
  2. a the log-rank test.
  3. b Major resection refers to lobectomy or pneumonectomy.