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Table 4 Comparison of the previous reports analyzing the perioperative change of serum CEA levels in patients with pathological stage-I NSCLC

From: Prognostic significance of postoperative serum carcinoembryonic antigen levels in patients with completely resected pathological-stage I non-small cell lung cancer

Author Okada[4] Matsuguma[11] Wang[15] Present study
Year 2004 2008 2010 2013
CEA measurement period Before surgery Within 1 M Within 1 M Within 2 W Within 1 M
After surgery Within 1 M Within 1–3 M Within 1–3 M Within 2 M
Cut-off point (ng/mL) 5.0 5.0 6.0 5.0
Total number 722 a 455 257 263
NN group (5-ys) 472 (84.2%) 323 (85.9%) 173 (71.1%) 198 (95.5%)
HN group 154 (74.2%) 112 (56.2%) 56 (54.6%) 44 (85.5%) b
HH group 96 (48.6%) 20 (43.1%) 28 (36.0%) 21 (59.3%)
Independent prognostic factor N/A Age Age Tumor diameter
Histology HH group VPI
VPI   HH group
HN/HH group   
  1. CEA, Carcinoembryonal antigen; NSCLC, Non-small cell lung cancer; M, Month; W, Week; N/A, Not analyzed; VPI, Visceral pleural invasion.
  2. a including incomplete resections.
  3. b 4-ys.