BMI ≥ 30 | BMI < 30 | P value | |
---|---|---|---|
Number (n) | 28 | 36 | |
Body mass index - Kg/M 2 (mean ± SD) | 33.4 ± 3.8 | 26.3 ± 3.1 | < 0.001 |
Age - years (mean ± SD) | 69.6 ± 6.8 | 65.5 ± 15.5 | 0.193 |
Male (%) | 20 (71.4) | 30 (83.3) | 0.278 |
Coronary response | |||
Passive diameter - μm (mean ± SEM) | 111.3 ± 5.5 | 118.1 ± 5.0 | 0.369 |
Bradykinin response [E -8 M] -% dilation (mean ± SEM) | 54.6 ± 4.7 | 45.9 ± 4.7 | 0.199 |
Underlying disease | |||
Diabetes mellitus (%) | 13 (46.4) | 17 (47.2) | 0.950 |
Hypertension (%) | 25 (89.3) | 31 (86.1) | 0.672 |
Coronary artery disease (%) | 13 (46.4) | 18 (50.0) | 0.886 |
Hypercholesterolemia (%) | 22 (78.6) | 26 (72.2) | 0.691 |
Surgery | |||
Coronary artery bypass graft (%) | 25 (89.3) | 25 (69.4) | 0.049 |
Aortic valve replacement (%) | 4 (14.3) | 18 (50.0) | 0.003 |
Mitral valve replacement (%) | 1 (2.8) | 0 (0.0) | 0.374 |
Medications | |||
ACE inhibitor (%) | 8 (28.6) | 20 (55.6) | 0.040 |
Angiotensin receptor blocker (%) | 13 (46.4) | 10 (27.8) | 0.144 |
Aspirin (%) | 23 (82.1) | 27 (75.0) | 0.456 |
Statin (%) | 15 (53.6) | 26 (72.2) | 0.087 |
Insulin (%) | 6 (21.4) | 7 (19.4) | 0.889 |
Anti-diabetics (%) | 6 (21.4) | 7 (19.4) | 0.889 |
Beta blocker (%) | 25 (89.3) | 21 (58.3) | 0.009 |
Diuretic (%) | 6 (21.4) | 15 (41.7) | 0.073 |
Calcium channel blocker (%) | 13 (46.4) | 16 (44.4) | 0.955 |
H+ blocker (%) | 11 (39.3) | 6 (16.7) | 0.049 |
Nitrate (%) | 8 (28.6) | 4 (11.1) | 0.085 |