|
Number (n)
|
28
|
36
| |
|
Body mass index - Kg/M
2
(mean ± SD)
|
33.4 ± 3.8
|
26.3 ± 3.1
|
< 0.001
|
|
Age - years (mean ± SD)
|
69.6 ± 6.8
|
65.5 ± 15.5
|
0.193
|
|
Male (%)
|
20 (71.4)
|
30 (83.3)
|
0.278
|
|
Coronary response
| | | |
|
Passive diameter - μm (mean ± SEM)
|
111.3 ± 5.5
|
118.1 ± 5.0
|
0.369
|
|
Bradykinin response [E
-8
M] -% dilation (mean ± SEM)
|
54.6 ± 4.7
|
45.9 ± 4.7
|
0.199
|
|
Underlying disease
| | | |
|
Diabetes mellitus (%)
|
13 (46.4)
|
17 (47.2)
|
0.950
|
|
Hypertension (%)
|
25 (89.3)
|
31 (86.1)
|
0.672
|
|
Coronary artery disease (%)
|
13 (46.4)
|
18 (50.0)
|
0.886
|
|
Hypercholesterolemia (%)
|
22 (78.6)
|
26 (72.2)
|
0.691
|
|
Surgery
| | | |
|
Coronary artery bypass graft (%)
|
25 (89.3)
|
25 (69.4)
|
0.049
|
|
Aortic valve replacement (%)
|
4 (14.3)
|
18 (50.0)
|
0.003
|
|
Mitral valve replacement (%)
|
1 (2.8)
|
0 (0.0)
|
0.374
|
|
Medications
| | | |
|
ACE inhibitor (%)
|
8 (28.6)
|
20 (55.6)
|
0.040
|
|
Angiotensin receptor blocker (%)
|
13 (46.4)
|
10 (27.8)
|
0.144
|
|
Aspirin (%)
|
23 (82.1)
|
27 (75.0)
|
0.456
|
|
Statin (%)
|
15 (53.6)
|
26 (72.2)
|
0.087
|
|
Insulin (%)
|
6 (21.4)
|
7 (19.4)
|
0.889
|
|
Anti-diabetics (%)
|
6 (21.4)
|
7 (19.4)
|
0.889
|
|
Beta blocker (%)
|
25 (89.3)
|
21 (58.3)
|
0.009
|
|
Diuretic (%)
|
6 (21.4)
|
15 (41.7)
|
0.073
|
|
Calcium channel blocker (%)
|
13 (46.4)
|
16 (44.4)
|
0.955
|
|
H+ blocker (%)
|
11 (39.3)
|
6 (16.7)
|
0.049
|
|
Nitrate (%)
|
8 (28.6)
|
4 (11.1)
|
0.085
|
