Table 3 Coronary dilations stratified by medications commonly prescribed to patients in obese or non-obese patients
BMI ≥ 30 | BMI < 30 | |||||
|---|---|---|---|---|---|---|
Bradykinin response [10-8M] -% dilation (Std. Error) | Bradykinin response [10-8M] -% dilation (Std. Error) | |||||
(+) Drug | (-) Drug | P Value | (+) Drug | (-) Drug | P Value | |
ACE inhibitor | 63.5 (9.5) | 51.0 (5.3) | 0.237 | 33.5 (6.2) | 58.2 (5.8) | 0.007 |
Angiotensin receptor blocker | 55.1 (6.1) | 54.1 (7.2) | 0.919 | 64.4 (8.1) | 36.9 (5.1) | 0.007 |
Aspirin | 57.1 (4.8) | 43.1 (14.6) | 0.261 | 49.2 (5.3) | 30.5 (9.2) | 0.086 |
Statin | 58.3 (4.7) | 50.4 (8.6) | 0.412 | 53.7 (5.1) | 20.1 (6.0) | 0.001 |
Insulin | 48.3 (7.6) | 56.3 (5.6) | 0.492 | 57.9 (10.3) | 41.3 (5.2) | 0.165 |
Anti-diabetics | 62.0 (23.0) | 52.6 (5.1) | 0.424 | 46.2 (11.5) | 44.1 (5.3) | 0.867 |
Beta blocker | 89.3% of obese patients are on beta blockers; test not valid | 51.5 (5.7) | 34.8 (7.6) | 0.081 | ||
Diuretic | 50.3 (9.8) | 55.8 (5.4) | 0.641 | 52.3 (6.0) | 38.9 (6.7) | 0.166 |
Calcium channel blocker | 55.8 (7.6) | 53.5 (6.1) | 0.811 | 38.6 (7.2) | 49.2 (6.2) | 0.267 |
H+ blocker | 62.0 (6.8) | 49.8 (62.6) | 0.210 | 45.8 (7.9) | 44.3 (5.5) | 0.907 |
Nitrate | 59.9 (8.6) | 52.5 (5.7) | 0.487 | 11.1% of non-obese patients are on nitrates; test not valid | ||