Table 1 Patient characteristics
All NSCLC | SCC | |||||||
|---|---|---|---|---|---|---|---|---|
Characteristic | Number (% of total) | Without tuber-culosis (%) | With tuber-culosis (%) | p-value | Number (% of SCC) | Without tuber-culosis (%) | With tuber-culosis (%) | p-value |
Number of subjects | 782(100) | 718(91.8) | 64(8.2) | 302(100) | 269(89.1) | 33(10.9) | ||
Age at diagnosis (years) (mean±SD) | 60±10.2 | 60±10.2 | 61±9.8 | 0.43 | 62±9.3 | 62±9.4 | 63±7.9 | 0.83 |
PS | 1.0 | 0.39 | ||||||
0 | 98 | 90 | 8 | 35 | 33 | 2 | ||
1 | 624 | 628 | 56 | 267 | 236 | 21 | ||
Sex | 0.06 | 0.13 | ||||||
Male | 600(76.7) | 545(75.9) | 55(85.9) | 285(94.4) | 252(93.7) | 33(100) | ||
Female | 182(23.3) | 173(24.1) | 9(14.1) | 17(5.6) | 17(6.3) | 0(0) | ||
Smoking status | 0.18 | 0.70 | ||||||
Never | 240(30.7) | 225(31.3) | 15(23.4) | 48(15.9) | 42(15.6) | 6(18.2) | ||
Smoker or ex-smoker | 542(69.3) | 493(68.7) | 49(76.6) | 254(84.1) | 227(84.4) | 27(81.8) | ||
Stage of lung cancer at diagnosis c | 0.18 | 0.16 | ||||||
I | 315(40.3) | 287(40.0) | 28(43.8) | 123(40.7) | 114(42.4) | 9(27.3) | ||
II | 157(20.1) | 141(19.6) | 16(25.0) | 60(19.9) | 50(18.6) | 10(30.3) | ||
III | 246(31.5) | 227(30.6) | 19(29.7) | 110(36.4) | 96(35.7) | 14(42.4) | ||
IV | 64(8.2) | 63(8.8) | 1(1.6) | 9(3.0) | 9(3.3) | 0(0.0) | ||
Histologic type | 0.06 | |||||||
SCC | 302(38.6) | 269(37.5) | 33(51.6) | |||||
Adenocarcinoma | 406(51.9) | 378(52.6) | 28(43.8) | |||||
Other a | 74(9.5) | 71(9.9) | 3(4.7) | |||||
Surgical approach | 0.10 | 0.07 | ||||||
Lobectomy | 685(87.6) | 633(88.2) | 52(81.2) | 245(81.1) | 222(82.5) | 23(69.7) | ||
Pneumonectomy | 97(12.4) | 85(11.8) | 12(18.8) | 57(18.9) | 47(17.5) | 10(30.3) | ||
Median survival (year) | 3.4 | 3.4 | 3.0 | 0.50 | 3.2 | 3.4 | 1.7 | <0.01b |