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Table 3 Adjusted effect of plasty procedure versus replacement controlling for confounders and level of interaction (effect modification)

From: Outcome of mitral valve plasty or replacement: atrial fibrillation an effect modifier

Using the Cox’s regression model
Total mortality    
Variables Level RR with 95% CL P-value
MPL/MVR Yes/No 0.43(0.28-0.74) 0.002
3 vessels CHD Yes/No 2.74(1.59-4.59) 0.0001
Reopration    
MPL/MVR Yes/No 0.32(0.13-0.81) 0.017
AF Yes/No 0.47(0.15-1.47) 0.198
AF*(MPL/MVR) Interaction 5.6(1.21-26.6) 0.028
Presence significant CHD Yes/no 0.47(0.19-1.14) 0.091
Using the Cox’s model stratified by propensity score quintiles
Total mortality    
Variables Level RR with 95% CL P-value
MPL/MVR Yes/no 0.54(0.32-0.90) 0.02
3 V CHD Yes/no 2.58(1.50-4.43) 0.001
Reoperation    
MPL/MVR Yes/no 0.75(0.32-1.72) 0.502
Sig. CHD Yes/no 0.46(017–1.21) 0.1190
  1. Interaction between MPL/MVR and AF:
  2. Absence of AF: RR = 0.32 95% (0.13-0.81) p = 0.017.
  3. Presence of AF: RR = 1.82 95% (0.52-6.4) p = 0.344.
  4. As presence of AF is part of the propensity score. Interaction between MREP and AF could not be performed.
  5. Sig. CHD: Presence of significant coronary artery stenosis > 50% in one of the major coronary artery.