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Table 2 TG parameters on T1 and T2, and their association with postoperative blood los

From: Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article

 

T1 (N=29)

T2 (N=29)

T1

T2

ROC analysis

Group 1 (N=14)

Group 2 (N=15)

p

Group 1 (N=14)

Group 2 (N=15)

p

T1 AUC

T2 AUC

PRP:

          

Lag time (min)

8.7 ± 3.0

8.7 ± 3.2

7.9 ± 1.4

9.4 ± 3.8

0.186

9.0 ± 3.1

8.5 ± 3.4

0.700

0.452 (0.232-0.672)

0.543 (0.322-0.764)

ETP (nM* min)

1881 ± 359

1524 ± 264

2104 ± 207

1672 ± 348

0.000

1649 ± 197

1407 ± 270

0.011

0.881 (0.741-1.021)

0.800 (0.630-0.970)

Peak (nM)

133 ± 42

73 ± 19

155 ± 30

112 ± 42

0.004

82 ± 18

64 ± 17

0.010

0.855 (0.697-1.013)

0.776 (0.605-0.947)

Time to peak (min)

19.3 ± 4.8

20.3 ± 5.6

18.4 ± 3.5

20.2 ± 5.7

0.315

20.1 ± 5.4

20.5 ± 6.0

0.870

0.381 (0.170-0.592)

0.493 (0.273-0.713)

PPP:

          

Lag time (min)

2.5 ± 0.5

4.2 ± 0.9

2.4 ± 0.4

2.6 ± 0.6

0.368

4.2 ± 1.0

4.1 ± 0.9

0.926

0.450 (0.236-0.664)

0.502 (0.287-0.718)

ETP (nM*min)

1587 ± 355

1508 ± 297

1774 ± 279

1412 ± 336

0.004

1610 ± 246

1411 ± 315

0.070

0.805 (0.639-0.971)

0.690 (0.493-0.888)

Peak (nM)

321 ± 63

241 ± 36

350 ± 48

295 ± 64

0.014

254 ± 31

230 ± 36

0.070

0.771 (0.597-0.946)

0.700 (0.312-0.745)

Time to peak (min)

4.7 ± 0.7

6.7 ± 1.1

4.6 ± 0.4

4.8 ± 0.9

0.532

6.8 ± 1.3

6.6 ± 1.0

0.588

0.502 (0.282-0.723)

0.529 (0.312-0.745)

  1. Data shown are mean ± SD. Comparison between the groups was done with student t-test. T1 before heparinisation, T2 after protamine administration, AUC area under the curve, ETP endogenous thrombin potential, PPP platelet poor plasma, PRP platelet rich plasma, ROC receiver operating curve.