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Table 2 TG parameters on T1 and T2, and their association with postoperative blood los

From: Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article

  T1 (N=29) T2 (N=29) T1 T2 ROC analysis
Group 1 (N=14) Group 2 (N=15) p Group 1 (N=14) Group 2 (N=15) p T1 AUC T2 AUC
PRP:           
Lag time (min) 8.7 ± 3.0 8.7 ± 3.2 7.9 ± 1.4 9.4 ± 3.8 0.186 9.0 ± 3.1 8.5 ± 3.4 0.700 0.452 (0.232-0.672) 0.543 (0.322-0.764)
ETP (nM* min) 1881 ± 359 1524 ± 264 2104 ± 207 1672 ± 348 0.000 1649 ± 197 1407 ± 270 0.011 0.881 (0.741-1.021) 0.800 (0.630-0.970)
Peak (nM) 133 ± 42 73 ± 19 155 ± 30 112 ± 42 0.004 82 ± 18 64 ± 17 0.010 0.855 (0.697-1.013) 0.776 (0.605-0.947)
Time to peak (min) 19.3 ± 4.8 20.3 ± 5.6 18.4 ± 3.5 20.2 ± 5.7 0.315 20.1 ± 5.4 20.5 ± 6.0 0.870 0.381 (0.170-0.592) 0.493 (0.273-0.713)
PPP:           
Lag time (min) 2.5 ± 0.5 4.2 ± 0.9 2.4 ± 0.4 2.6 ± 0.6 0.368 4.2 ± 1.0 4.1 ± 0.9 0.926 0.450 (0.236-0.664) 0.502 (0.287-0.718)
ETP (nM*min) 1587 ± 355 1508 ± 297 1774 ± 279 1412 ± 336 0.004 1610 ± 246 1411 ± 315 0.070 0.805 (0.639-0.971) 0.690 (0.493-0.888)
Peak (nM) 321 ± 63 241 ± 36 350 ± 48 295 ± 64 0.014 254 ± 31 230 ± 36 0.070 0.771 (0.597-0.946) 0.700 (0.312-0.745)
Time to peak (min) 4.7 ± 0.7 6.7 ± 1.1 4.6 ± 0.4 4.8 ± 0.9 0.532 6.8 ± 1.3 6.6 ± 1.0 0.588 0.502 (0.282-0.723) 0.529 (0.312-0.745)
  1. Data shown are mean ± SD. Comparison between the groups was done with student t-test. T1 before heparinisation, T2 after protamine administration, AUC area under the curve, ETP endogenous thrombin potential, PPP platelet poor plasma, PRP platelet rich plasma, ROC receiver operating curve.