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Table 3 Laboratory parameters on T1 and T2, and their association with postoperative blood loss

From: Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article

  T1 (N=29) T2 (N=29) T1 T2 ROC analysis
Group 1 (N=14) Group 2 (N=15) p Group 1 (N=14) Group 2 (N=15) p T1 AUC (95% CI) T2 AUC (95% CI)
Hemoglobin (mmol/l) 7.8 ± 0.6 5.4 ± 0.5 7.7 ± 0.5 7.8 ± 0.8 0.435 5.6 ± 0.5 5.3 ± 0.4 0.098 0.377 (0.165-0.590) 0.714 (0.517-0.912)
Hematocrit (%) 37.2 ± 3.3 25.9 ± 2.3 36.8 ± 2.6 37.7 ± 3.8 0.475 26.8 ± 2.2 25.1 ± 2.2 0.044 0.401 (0.186-0.617) 0.732 (0.540-0.924)
Platelet number (*109/l) 215 ± 61 128 ± 42 249 ± 57 184 ± 48 0.002 152 ± 40 105 ± 31 0.002 0.834 (0.690-0.979) 0.857 (0.705-1.009)
Fibrinogen (g/l) 2.9 ± 0.7 1.7 ± 0.4 3.1 ± 0.8 2.7 ± 0.5 0.198 1.9 ± 0.5 1.5 ± 0.3 0.045 0.627 (0.419-0.835) 0.703 (0.512-0.894)
D-dimers (ng/ml) 700 ± 782 1109 ± 1146 949 ± 1063 467 ± 235 0.119 1083 ± 1069 1132 ± 1251 0.909 0.654 (0.442-0.866) 0.547 (0.333-0.761)
Antithrombin (%) 80.9 ± 11.5 49.6 ± 6.6 80.1 ± 7.8 81.6 ± 14.4 0.727 50.1 ± 7.1 49.0 ± 6.3 0.651 0.440 (0.229-0.651) 0.574 (0.364-0.783)
PT (sec) 11.5 ± 0.5 15.4 ± 1.5 11.4 ± 0.6 11.5 ± 0.4 0.417 15.2 ± 1.3 15.7 ± 1.6 0.341 0.425 (0.205-0.646) 0.373 (0.168-0.577)
aPTT (sec) 28.9 ± 3.2 34.6 ± 5.5 28.9 ± 3.9 28.8 ± 2.7 0.922 34.1 ± 5.6 35.1 ± 5.5 0.634 0.498 (0.276-0.719) 0.406 (0.197-0.615)
ACT (sec) 132 ± 15 140 ± 17 134 ± 18 131 ± 12 0.625 140 ± 15 141 ± 19 0.875 0.498 (0.281-0.714) 0.487 (0.275-0.698)
  1. Data shown are mean ± SD. Comparison between the groups was done with student t-test. T1 before heparinisation, T2 after protamine administration, ACT activated clotting time, aPTT activated partial thromboplastin time, PT prothrombin time.