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Table 3 Laboratory parameters on T1 and T2, and their association with postoperative blood loss

From: Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article

 

T1 (N=29)

T2 (N=29)

T1

T2

ROC analysis

Group 1 (N=14)

Group 2 (N=15)

p

Group 1 (N=14)

Group 2 (N=15)

p

T1 AUC (95% CI)

T2 AUC (95% CI)

Hemoglobin (mmol/l)

7.8 ± 0.6

5.4 ± 0.5

7.7 ± 0.5

7.8 ± 0.8

0.435

5.6 ± 0.5

5.3 ± 0.4

0.098

0.377 (0.165-0.590)

0.714 (0.517-0.912)

Hematocrit (%)

37.2 ± 3.3

25.9 ± 2.3

36.8 ± 2.6

37.7 ± 3.8

0.475

26.8 ± 2.2

25.1 ± 2.2

0.044

0.401 (0.186-0.617)

0.732 (0.540-0.924)

Platelet number (*109/l)

215 ± 61

128 ± 42

249 ± 57

184 ± 48

0.002

152 ± 40

105 ± 31

0.002

0.834 (0.690-0.979)

0.857 (0.705-1.009)

Fibrinogen (g/l)

2.9 ± 0.7

1.7 ± 0.4

3.1 ± 0.8

2.7 ± 0.5

0.198

1.9 ± 0.5

1.5 ± 0.3

0.045

0.627 (0.419-0.835)

0.703 (0.512-0.894)

D-dimers (ng/ml)

700 ± 782

1109 ± 1146

949 ± 1063

467 ± 235

0.119

1083 ± 1069

1132 ± 1251

0.909

0.654 (0.442-0.866)

0.547 (0.333-0.761)

Antithrombin (%)

80.9 ± 11.5

49.6 ± 6.6

80.1 ± 7.8

81.6 ± 14.4

0.727

50.1 ± 7.1

49.0 ± 6.3

0.651

0.440 (0.229-0.651)

0.574 (0.364-0.783)

PT (sec)

11.5 ± 0.5

15.4 ± 1.5

11.4 ± 0.6

11.5 ± 0.4

0.417

15.2 ± 1.3

15.7 ± 1.6

0.341

0.425 (0.205-0.646)

0.373 (0.168-0.577)

aPTT (sec)

28.9 ± 3.2

34.6 ± 5.5

28.9 ± 3.9

28.8 ± 2.7

0.922

34.1 ± 5.6

35.1 ± 5.5

0.634

0.498 (0.276-0.719)

0.406 (0.197-0.615)

ACT (sec)

132 ± 15

140 ± 17

134 ± 18

131 ± 12

0.625

140 ± 15

141 ± 19

0.875

0.498 (0.281-0.714)

0.487 (0.275-0.698)

  1. Data shown are mean ± SD. Comparison between the groups was done with student t-test. T1 before heparinisation, T2 after protamine administration, ACT activated clotting time, aPTT activated partial thromboplastin time, PT prothrombin time.