Table 1 The classification of histomorphological changes of the endothelial layer
From: Effects of temporary vascular occluder poloxamer 407 Gel on the endothelium
Damage type | Histomorphological features |
|---|---|
No damage | The endothelial cells are contact with each other, neither change in the cellular morphology nor any decrease in size. |
Type 1 damage | Cellular integrity of endothelial cells is unchanged. Endothelial cells are in contact with each other, but the flattening of the endothelial cells, changes in diameter and the occurrence of the nuclei. In addition, the adhesion of blood cells on the endothelium. |
Type 2 damage | Detachment of the cells at their junction points and/or isolated absence of endothelial cells. |
Type 3 damage | Appearance of the subendothelial tissue with desquamation of endothelial cells. |