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Table 2 Results of univariate and multivariate analyses based on observed late (deaths within 30 days of aortic valve replacement excluded) survival using the cox regression

From: Obesity and the risk of late mortality after aortic valve replacement with small prosthesis

  Univariate analysis Multivariate analysis 2
  p Value HR (95% CI) p Value HR (95% CI)
Age p < 0.001 1.34(1.12-1.58) p < 0.001 1.21(1.04-1.10)
Sex 0.08 0.92(0.72-1.14) 0.21 0.89(0.84-0.95)
Body surface area NS 1.34(1.14-1.53) 0.75 1.29(1.10-1.50)
NYHA functional calss III/IV p < 0.001 1.25(1.04-1.47) 0.48 1.22(1.01-1.43)
LVEF p < 0.001 1.58(1.12-2.06) p < 0.001 1.28(1.09-1.51)
Predominant AS 0.05 1.11(0.84-1.40) 0.43 1.04(0.86-1.24)
Diabetes mellitus p < 0.001 1.21(1.02-1.12) 0.01 1.02(0.75-1.32)
Systemic hypertension p < 0.001 1.43(0.14-1.78) p < 0.001 1.20(0.87-1.53)
Chronic lung disease p < 0.001 1.39(1.20-1.63) 0.003 1.30(1.03-1.60)
AF p < 0.001 1.27(1.04-1.56) 0.12 1.16(0.89-1.48)
Operative data     
Concomitant CABG 0.004 1.10(0.96-1.26) 0.11 1.02(0.90-1.15)
EOAI ≤ 0.85 cm2/m2 p < 0.001 1.42(1.12-1.73) 0.005 1.26(1.09-1.44)
Mechanical prosthesis 0.03 1.17(0.94-1.42) 0.08 0.88(0.65-1.10)
24 ≤ BMI ≤ 27.9 0.01 0.92(0.71-1.15) 0.34 0.68(0.50-0.92)
BMI ≥ 28 p < 0.001 1.84(1.46-2.26) 0.01 1.62(1.33-1.93)
Propensity score 0.75 1.51(1.18-1.94) 0.53 1.73(1.34-2.12)
  1. Bold indicates statistical significance on multivariate analysis. Analysis 1: without adjustment for propensity score. Analysis 2: with adjustment for propensity score. CI, Confidence interval; HR, Hazard ratio; AS, Aortic stenosis; BMI, Body mass index; other abbreviations as in Table 1.