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Table 2 Results of univariate and multivariate analyses based on observed late (deaths within 30 days of aortic valve replacement excluded) survival using the cox regression

From: Obesity and the risk of late mortality after aortic valve replacement with small prosthesis

 

Univariate analysis

Multivariate analysis 2

 

p Value

HR (95% CI)

p Value

HR (95% CI)

Age

p < 0.001

1.34(1.12-1.58)

p < 0.001

1.21(1.04-1.10)

Sex

0.08

0.92(0.72-1.14)

0.21

0.89(0.84-0.95)

Body surface area

NS

1.34(1.14-1.53)

0.75

1.29(1.10-1.50)

NYHA functional calss III/IV

p < 0.001

1.25(1.04-1.47)

0.48

1.22(1.01-1.43)

LVEF

p < 0.001

1.58(1.12-2.06)

p < 0.001

1.28(1.09-1.51)

Predominant AS

0.05

1.11(0.84-1.40)

0.43

1.04(0.86-1.24)

Diabetes mellitus

p < 0.001

1.21(1.02-1.12)

0.01

1.02(0.75-1.32)

Systemic hypertension

p < 0.001

1.43(0.14-1.78)

p < 0.001

1.20(0.87-1.53)

Chronic lung disease

p < 0.001

1.39(1.20-1.63)

0.003

1.30(1.03-1.60)

AF

p < 0.001

1.27(1.04-1.56)

0.12

1.16(0.89-1.48)

Operative data

    

Concomitant CABG

0.004

1.10(0.96-1.26)

0.11

1.02(0.90-1.15)

EOAI ≤ 0.85 cm2/m2

p < 0.001

1.42(1.12-1.73)

0.005

1.26(1.09-1.44)

Mechanical prosthesis

0.03

1.17(0.94-1.42)

0.08

0.88(0.65-1.10)

24 ≤ BMI ≤ 27.9

0.01

0.92(0.71-1.15)

0.34

0.68(0.50-0.92)

BMI ≥ 28

p < 0.001

1.84(1.46-2.26)

0.01

1.62(1.33-1.93)

Propensity score

0.75

1.51(1.18-1.94)

0.53

1.73(1.34-2.12)

  1. Bold indicates statistical significance on multivariate analysis. Analysis 1: without adjustment for propensity score. Analysis 2: with adjustment for propensity score. CI, Confidence interval; HR, Hazard ratio; AS, Aortic stenosis; BMI, Body mass index; other abbreviations as in Table 1.