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Figure 4 | Journal of Cardiothoracic Surgery

Figure 4

From: Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile

Figure 4

Effect of human sera on virus transduction. A. A549 cells were infected with a range of vp/cell as indicated. β-Gal activity was normalised to total protein levels. B-C. A549 cells were infected with 10,000 vp/cell B. Ad5, C. Ad5T*F35++ in the presence of 2.5% human sera. β-Gal activity was measured 48 hours post infection and normalised to total protein levels. Graphs show the relative change in transduction compared to no serum control. The red line indicates 90% inhibition of virus transduction compared to no serum control sample.

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