Skip to main content

Table 5 Receiver operating characteristic curves for predicting and monitoring fluid responsiveness

From: Mixed venous O2 saturation and fluid responsiveness after cardiac or major vascular surgery

  AUC P Cutoff Sens. Spec. PPV NPV
  (95% confidence interval)       
For increase in CI ≥15%
SvO2, % 0.65 (0.44 to 0.86) 0.17 77     
Change in SvO2, % 0.73 (0.56 to 0.86) 0.007 2 77 73 87 57
GEDVI, mL/m2 0.67 (0.47 to 0.88) 0.10 899 68 70 81 54
Change in GEDVI, mL/m2 0.82 (0.65 to 1.0) <0.001 13 95 60 82 86
For increase in SVI ≥15%
SvO2, % 0.60 (0.40 to 0.81) 0.29 77 87 50 74 70
Change in SvO2, % 0.68 (0.50 to 0.82) 0.04 2 78 64 78 64
GEDVI, mL/m2 0.58 (0.38 to 0.76) 0.48 899 69 62 69 62
Change in GEDVI, mL/m2 0.83 (0.65 to 0.94) <0.001 92 75 92 92 75
For increase in CI ≥15% at high and low GEF
Change in SvO2, %
GEF >20% 0.57 (0.23 to 0.92) 0.68 3 0 71 0 42
GEF ≤20% 0.94 (0.81 to 1.0) <0.001 2 92 100 100 95
GEDVI, mL/m2
GEF >20% 0.80 (0.53 to 1.0) 0.02 755 71 86 83 75
GEF ≤20% 0.81 (0.58 to 1.0) 0.008 1028 75 100 100 50
Change in GEDVI, mL/m2
GEF >20% 0.76 (0.47 to 0.94) 0.10 49 86 71 75 83
GEF ≤20% 0.92 (0.73 to 1.0) <0.001 92 75 100 100 50